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Associations between comorbidities and survival outcomes in older adults with cancer: a scoping review of international and Japanese evidence
CONCLUSIONS: Comorbidities were consistently associated with poorer survival outcomes among older adults with cancer. International and Japanese studies appeared to emphasize different mechanisms linking comorbidities to prognosis; however, these differences should be interpreted cautiously owing to heterogeneity in study design, outcome definitions, and data sources. Further large-scale studies incorporating standardized comorbidity assessment are needed to clarify the mechanisms through which...
Implementing cognitive training in primary health care for older adults with MCI: study protocol for a type 3 hybrid effectiveness-implementation cluster-randomized factorial trial
BACKGROUND: Dementia prevention is an urgent global health priority in aging populations. Mild cognitive impairment (MCI) presents a key window for intervention, where cognitive training can effectively slow progression to dementia. There remains a need for implementation strategies that activate primary healthcare providers (the first point of contact) to deliver such interventions. This study aims to evaluate a multi‑component implementation strategy (enhanced training, financial incentives,...
Just 4 minutes a day can dramatically improve strength after 65
A new Penn State study suggests that just four minutes of daily strength training can significantly improve mobility and physical function in older adults. After 12 weeks, participants showed meaningful gains in balance, leg strength, and their ability to stand up from a chair, all important factors for maintaining independence and reducing fall risk.