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Why we need an International Panel on Inequality
Medicines do no good if people don’t take them
Drug-delivering particles aim to breach the blood–brain barrier
Special delivery: bacterial couriers are smuggling drugs into cancers
These six advances could change how drugs are delivered
Why the super-fun Ig Nobel prizes bring serious value to science
In the basement of miniaturized relics
Bacteria recruited to treat cancer
How AI is changing PhD programmes: join our free webinar
DeepMind’s new genome ‘atlas’ charts effects of all nine billion human gene mutations
Italian hunting bill will sideline science, critics say
New legislation would loosen regulations and reduce the role of an environmental research body in decisions affecting wildlife
Need <em>Help!</em> writing a paper title? All you need is the Beatles
At least 3200 scientific publications refer to the Fab Four’s music—by far the most of any top-selling artist
Pangaea’s ‘little brother’ may finally qualify as a supercontinent
New evidence suggests Gondwana was far larger than previously thought, challenging models of continental cycling
Conference posters could garner a wider audience, thanks to a new online platform
The staple format also warrants a deeper rethink, some researchers say
Caffeine may flip an ancient cellular switch linked to slower aging
Scientists found that caffeine activates an ancient cellular energy system involved in stress resistance, DNA repair, and growth. The discovery could help explain caffeine’s links to healthier aging and may point toward new ways to target the same pathway.
Scientists discover a powerful new antivenom hidden in rattlesnake blood
Researchers discovered that combinations of toxin-blocking proteins naturally found in rattlesnake blood can powerfully neutralize venom from several dangerous snake species. In lab tests, the mixtures were about 10 times more potent than a current commercial antivenom, pointing toward a new generation of nature-inspired snakebite treatments.
Your personality may be more genetic than scientists realized
More than 1,200 genetic variants have been linked to the Big Five personality traits, and many of the same variants are also associated with health, longevity, careers, income, and everyday habits. The findings reveal a surprisingly wide genetic connection between personality and life outcomes while showing that environment still plays a powerful role.
Ozempic and Wegovy may have an unexpected mental health benefit
Semaglutide, the drug behind Ozempic and Wegovy, may have benefits that extend well beyond weight loss and diabetes. In a large Swedish study of nearly 15,000 people with bipolar disorder, its use was linked to a 21% lower risk of psychiatric hospitalization. Researchers think effects on inflammation and brain-related biological pathways could help stabilize mood, though other GLP-1 drugs did not show the same association.
Scientists observe Einstein’s gravity in the quantum world for the first time
Physicists have directly observed a long-predicted quantum effect of gravity, putting one of Einstein’s foundational ideas to a striking new test. Using ultracold atoms, researchers split an atom’s quantum wave so that one part was held in place while the other fell freely under gravity, then reunited the two to measure the tiny difference that emerged.
Scientists find a new weakness in treatment-resistant prostate cancer
Researchers have found a potential way to attack prostate cancers that evade treatment by changing their cellular identity. Combining two types of drugs reversed many of these changes and sharply slowed tumor growth in preclinical experiments, offering a possible new strategy for aggressive, treatment-resistant disease.