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Scientists find a natural gut compound that helps heal the intestine

13 hours 45 minutes ago
A natural compound produced by gut bacteria after digesting foods such as pomegranates, walnuts, and berries may help repair and protect the intestinal lining. The discovery reveals a surprising beneficial side of an inflammatory pathway and could inspire more targeted treatments for Crohn’s disease and ulcerative colitis.

Life Course Neighborhood Socioeconomic Disadvantage and Chronic Disease Accumulation in Mid- to Late Adulthood

14 hours 59 minutes ago
ObjectiveThis study examines associations between neighborhood socioeconomic disadvantage during adolescence and early adulthood and chronic disease accumulation in mid- to late life.MethodsUsing Panel Study of Income Dynamics data linked to U.S. Census and American Community Survey data, we identify four trajectories of neighborhood disadvantage, namely persistent disadvantage, increasing disadvantage, decreasing disadvantage, and persistent advantage, and estimate their associations with...
Ying Huang

New mesothelioma drug turns cancer’s own defenses against it

19 hours 47 minutes ago
Scientists are testing a counterintuitive way to fight mesothelioma, an aggressive asbestos-linked cancer with few effective treatments. A new experimental mesothelioma drug kills cancer cells by disabling PRX3, an antioxidant defense that tumors use to survive intense oxidative stress. In an early clinical trial, it controlled disease progression in 67% of patients and produced encouraging survival results, raising hopes that the strategy could eventually be used against other cancers.

Scientists find an immune “false alarm” that may drive rapid aging

1 day 10 hours ago
Scientists have discovered that some severe genetic disorders linked to rapid aging may be driven not just by damaged DNA, but by the body’s overreaction to that damage. When broken DNA fragments leak into the wrong part of a cell, an immune sensor called cGAS can mistake them for signs of a viral infection, triggering chronic inflammation and even interfering with DNA repair itself.