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Without intervention, NSF could fully close the Social, Behavioral and Economic Sciences Directorate in a month

Scientists have discovered that pantethine, a readily available vitamin B5 derivative, can calm overactive immune cells and may help fight psoriasis. The supplement prevented psoriasis in mice and showed promising results in a small human trial, revealing an unexpected connection between cholesterol and autoimmune inflammation.

Scientists have discovered that gut bacteria can feed on the protective mucus lining your intestines, producing potentially harmful compounds, but fiber helps keep this activity in check. Overlooked proteins in plant foods also help shift gut bacteria toward producing beneficial substances, revealing a surprising new reason plant-based diets may be good for you.

Blood-brain barrier (BBB) dysfunction is an early feature of brain aging, but the endothelial mechanisms preserving barrier resilience remain unclear. Although we have reported α-synuclein (SNCA) supports vascular endothelial homeostasis, its role in the brain microvascular endothelium is unknown. Because SNCA loss suppresses eNOS/NO signaling and promotes endothelial β-site amyloid precursor protein cleaving enzyme 1 (BACE1) induction, we investigated whether senescence-associated SNCA decline...

After more than 35 years of research, scientists have uncovered surprising clues about what really drives Lyme disease risk. Contrary to longstanding assumptions, deer populations appear less important than mice, which can fuel a 40% increase in tick numbers the following year. Even acorn production can predict tick population surges two years in advance, while extreme temperatures may be far less deadly to ticks than scientists once believed.

A surprising new study from UCLA suggests that a naturally occurring molecule could help breast cancer survivors overcome the frustrating brain fog and exhaustion that can linger long after treatment ends. Researchers found that women taking an oxaloacetate supplement for eight weeks experienced substantial improvements in memory, concentration, mental clarity, and fatigue.

New findings demonstrate AI’s aptitude for identifying technical flaws in studies where medical decisions are on the line

A massive study of more than 120,000 older adults suggests that common osteoporosis drugs may reduce the risk of Alzheimer’s disease and other dementias by up to 24%. The surprising findings raise the possibility that medications already used to strengthen bones could also help protect the aging brain.

Scientists have discovered that a buildup of a protein called Miro1 may be a hidden driver of insulin resistance in Type 2 diabetes, with preclinical experiments showing that removing it restores the muscles’ response to insulin. Exercise was also found to lower Miro1 levels in people with diabetes, revealing a potential new pathway for treating the disease.

Scientists at UC San Francisco have developed a powerful new cancer therapy that remains inactive until it reaches the brain, where it switches on to attack deadly tumors. The engineered immune cells, called B-SYNC CAR-T cells, completely eliminated diffuse midline glioma (DMG), an aggressive childhood brain cancer that is almost always fatal within a year, in two mouse models.

More than a century after Einstein revolutionized our understanding of gravity, scientists have uncovered a surprising new phenomenon hidden within his equations. Researchers at Columbia University and Universidad Adolfo Ibáñez have identified a theoretical process called "gravitational reconnection," in which structures within gravitational fields can break apart and reconnect, transferring energy into matter.

Scientists have discovered that fasting for just 24 hours increases a beneficial gut bacterium that helps the intestines regenerate after radiation damage. The preclinical findings could pave the way for new treatments that protect healthy tissue during cancer therapy, potentially without requiring patients to fast.