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Scientists say they’ve reversed brain aging with a simple nasal spray
Researchers at Texas A&M have developed a nasal spray that appears to reverse brain aging by calming inflammation and restoring the brain’s energy systems. After just two doses, memory and cognitive function improved for months, raising hopes for future treatments targeting dementia and brain fog.
Loss of Brain-Derived Estrogen Is Associated With Sex- and Age-Dependent Alterations in Memory, Affective Behavior, and Hippocampal Extracellular Matrix Gene Expression
Nearly two-thirds of Americans with Alzheimer's disease (AD) are women. Prior research suggested that women with AD have lower brain estrogen levels than those without AD. However, how estrogen deficiency modulates this sex-based difference in AD vulnerability is not well understood. Aromatase, the key enzyme for estrogen biosynthesis, is expressed in both neurons and astrocytes of the brain, including the hippocampus. This study aims to assess the mechanistic link between brain-selective...
Undermining older adults' autonomy impairs physical health: longitudinal evidence and psychological mechanisms
CONCLUSIONS: Undermined autonomy poses a significant independent threat to older adults' physical health and longevity. This detrimental effect is partly driven by the internalization of negative stereotypes regarding older adults' competence. Findings underscore the critical need to protect older adults' autonomy and challenge the infantilizing attitudes that often rationalize paternalistic practices.
Loss of Brain-Derived Estrogen Is Associated With Sex- and Age-Dependent Alterations in Memory, Affective Behavior, and Hippocampal Extracellular Matrix Gene Expression
Nearly two-thirds of Americans with Alzheimer's disease (AD) are women. Prior research suggested that women with AD have lower brain estrogen levels than those without AD. However, how estrogen deficiency modulates this sex-based difference in AD vulnerability is not well understood. Aromatase, the key enzyme for estrogen biosynthesis, is expressed in both neurons and astrocytes of the brain, including the hippocampus. This study aims to assess the mechanistic link between brain-selective...
Wikipedia’s gender gap has flipped for one group of scientists
A new study finds women biology faculty are now more likely than men to have a biography on the popular website
Robots run this laboratory in Japan — and are changing how scientists work
Hard-to-detect mutations explain how common autoimmune diseases arise
Should there be a national museum of chemicals?
Bottom-Up Synthesis of Molecular Nanodiamond from Nanographene
When the grid can’t keep up: how South African laboratories handle power outages
Why AI can’t be trusted to write scientific reviews
Innovation starts in schools — lessons from China
Too dangerous to release: is Mythos the start of the restricted-AI era?
Iran’s Internet blackout: a scholar’s month in the dark
A cautious voice on the closure of China’s journal ranking list
Conservation gains should not be at the mercy of political changes
Poland’s economy is thriving, but its science is dying
Author Correction: In vitro characterization of the human segmentation clock
USC scientists discover a hidden Alzheimer’s trigger and a possible way to shut it down
USC researchers have identified potential new drug compounds that may reduce the brain inflammation linked to Alzheimer’s disease, especially in people with the high-risk APOE4 gene. The compounds target cPLA2, an enzyme that seems to fuel harmful inflammation while also being important for normal brain activity.
Outdoor lights may be making mosquito season longer
Artificial light at night delays winter “shutdown” of mosquitoes carrying disease