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Cinematic geologists are usually good guys—sometimes gals—but they have a one in three fatality rate, a film analysis show

Hidden chambers may provide Mediterranean monk seals refuge from tourists

Cannabis use among older adults is rising fast, but today’s marijuana is far more potent than many people realize — and experts warn the risks may be underestimated. Stanford Medicine specialists say modern cannabis can increase the chances of heart problems, falls, memory issues, dangerous drug interactions, and even addiction, especially for people over 65.

Scientists have uncovered a surprising dark side to vitamin B2: it may help cancer cells stay alive. The vitamin supports a cellular shield that protects tumors from ferroptosis, a form of programmed cell death linked to cancer suppression. In lab tests, researchers used a vitamin B2-like compound called roseoflavin to break down that protection and trigger cancer cell death.

Scientists have uncovered evidence that serotonin — the same brain chemical boosted by many antidepressants — may actually worsen tinnitus. Using advanced light-based brain stimulation in mice, researchers identified a serotonin-driven circuit linked directly to tinnitus-like behavior. The findings may explain why some people experience louder ringing in their ears while taking SSRIs.

Relocating plants’ light-capturing structures to the eye may fight damage from dry eye

Researchers analyzing over 20,000 patients found that very high levels of the inherited cholesterol particle Lp(a) dramatically raise the risk of stroke, cardiovascular death, and major heart complications. Because most people with elevated Lp(a) have no symptoms, experts say a simple blood test could uncover a dangerous hidden risk factor.

SMILE orbiter will use x-rays to map how the solar wind batters the magnetosphere

Poly(ADP-ribose) (PAR) polymerase 1 (PARP1) has been implicated in DNA damage responses and neuroinflammation in Alzheimer's disease (AD), yet its role in amyloid-beta (Aβ) pathology remains unclear. Here, we show that PARP1 activation drives Aβ pathology and neurodegeneration. Using a sensitive enzyme-linked immunosorbent assay, we observed significantly elevated PAR levels in the cerebrospinal fluid (CSF) of patients with mild cognitive impairment (MCI) and AD compared to controls. In vitro,...

CONCLUSIONS: Self-reported driving concerns demonstrate predictive validity for future crashes, but a substantial minority of crash-involved drivers remain undetected by self-report. Education and TMT-B performance may serve as clinically actionable markers for identifying these "silent" at-risk drivers.

The global increase in neurodegenerative disorders such as Alzheimer's disease has prompted the search for effective non-pharmacological interventions. Chrono-exercise which is the physical training aligned with circadian rhythms has emerged as a novel strategy to strengthen cognitive resilience. This study explores the impact of chrono-exercises, incorporating aerobic, resistance, and combined modalities, performed at the early dark (ZT13) and early light (ZT1) phases in an aluminum chloride...