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Geologist and officials were acquitted last week, but scientists fear future liability for failing to predict similar disasters

Nighttime light exposure was linked to thicker, stiffer heart chambers and early signs of reduced heart function in a study of more than 11,000 people. The findings suggest that keeping bedrooms darker could be an overlooked strategy for protecting the heart.

A major Ontario study found 24 common medication chains in which one drug’s side effects can be mistaken for a new medical problem, leading to another prescription. Researchers say closer medication reviews, pharmacist involvement, and automated alerts could help prevent these potentially harmful prescribing cascades.

Researchers analyzing data from more than 1.9 million people found that ADHD is associated with substantially higher rates of digestive problems. People with ADHD had nearly double the odds of constipation, 58% higher odds of irritable bowel syndrome, and more than four times the odds of encopresis.

An evolutionary trade-off may have helped a mutation linked to auto-immune disease persist in human populations

Ovarian aging leads to permanent reproductive senescence and systemic hormonal changes that predispose women to age-associated comorbidities. Despite these observations, the intrinsic mechanisms driving age-related ovarian decline are poorly defined. Mitochondrial DNA (mtDNA) mutations and instability are strongly associated with aging; however, it remains unknown if naturally occurring mitochondrial genetic variation influences the trajectory of ovarian aging. To address this, we compared two...

Ultraviolet (UV)-induced skin photoaging is driven by cellular senescence and chronic inflammation. Although the secretome (SCT) derived from human umbilical cord mesenchymal stem cells (hUC-MSC SCT) exhibits regenerative potential, its role in combating photoaging remains to be elucidated. In this study, we show that SCT markedly ameliorates photoaging in UV-exposed mice, restoring epidermal barrier function, dermal collagen integrity, senescence-associated markers, and systemic inflammatory...

A remarkably detailed study of Maria Branyas, who lived past 117, reveals that extreme longevity may involve both intense aging and powerful biological protection at the same time. Researchers found signs of advanced aging, but also low inflammation, beneficial gut bacteria, protective genetic features, and a biological age younger than her chronological age. Because she avoided major disease, the study offered a rare look at aging itself rather than the illnesses that often accompany it.

Researchers have shown for the first time that human heart muscle cells can regrow after a heart attack. The finding overturns the idea that damaged areas of the heart are completely incapable of regeneration. Scientists now hope to identify ways to dramatically boost this natural repair process, potentially opening a new path toward treatments for heart failure.

Genesis Mission partnership between national labs and AI startup builds new model to automate large-scale science

Eating only between noon and 8 p.m. improved blood sugar control in a small study of adults with Type 1 diabetes and obesity, while avoiding an increase in serious complications. The promising findings offer the first evidence that time restricted eating could become another tool for managing the condition.

Science, Ahead of Print.

UCLA researchers developed ready-made cancer-fighting T cells from cord blood stem cells that can attack solid tumors through two separate detection systems. In mice, a single dose controlled cancer and extended survival while avoiding a dangerous complication associated with donor-derived T-cell therapies.