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Open-source AI program can answer science questions better than humans
Developed by and for academics, OpenScholar aims to improve searches of the ballooning scientific literature
Correction: Geroprotective effects of Salvianolic acid A through redox and detoxification pathway activation in an aging Drosophila Alzheimer's model
No abstract
Recommendations from the European interdisciplinary council on ageing on physical activity and diet for mental health conditions in older adults
The global rise in life expectancy is accompanied by an increase in the prevalence of mental health conditions among older adults, including mild cognitive impairment (MCI), dementia, delirium, depression, anxiety, and other severe mental illness. These conditions significantly impact independence, increase healthcare costs, and increase mortality risk. Mounting evidence underscores the central role of modifiable lifestyle factors-particularly physical activity and diet-in the prevention and...
Change in loneliness and subsequent cardiometabolic Multimorbidity among middle-aged and older adults: results from two east asian prospective cohorts
CONCLUSIONS: Changes in loneliness were associated with an increased risk of subsequent CMM in both China and South Korea, with the strongest associations observed among individuals experiencing persistent loneliness. These findings indicate that loneliness is a dynamic and potentially modifiable risk factor for cardiometabolic multimorbidity across different sociocultural contexts. Early identification and targeted interventions addressing loneliness may contribute to the prevention of CMM...
Flavonoid intake and telomere length attrition among middle-aged women: a cross-sectional analysis of the Nurses' Health Study
Although mechanistic studies support a beneficial effect of several dietary flavonoids on telomere length (TL), to our knowledge no studies have examined associations between habitual flavonoid intakes and TL in population-based studies. We examined the associations between habitual intake of major flavonoid subclasses (flavonols, flavones, flavanones, flavan-3-ols and their polymers, and anthocyanins) and TL in a cross-sectional analysis of 4,944 disease-free females from the Nurses' Health...
Increased Risk of Transition to Institutional Care Among Community-Dwelling Older Adults With Cognitive Frailty: A Competing Risks Survival Analysis
CONCLUSION: Our findings demonstrated the positive association between CF and TIC, highlighting the need for appropriate and timely management of CF and personalised interventions for this vulnerable group to delay premature institutionalisation.
Psychosocial and Health Factors Associated With Functional Difficulties Among Older U.S. Veterans With Cardiovascular Disease
ObjectivesOlder U.S. military veterans with cardiovascular disease (CVD) are at elevated risk for functional decline. This study examined sociodemographic, health, and psychosocial correlates of overall and domain-specific functioning in this population.MethodsData were drawn from 757 veterans aged ≥60 years with CVD who participated in the National Health and Resilience in Veterans Study. Bivariate, multivariable, and relative importance analyses were used to identify key correlates of...