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Why the same DNA damage causes cancer in some people but not others
A controlled mouse study has provided direct evidence that inherited genetics can steer how cancer begins and evolves after DNA damage. The discovery could eventually help doctors better predict cancer risk and tailor screening and treatments to each patient.
Daily briefing: The town heated by one big battery
‘Timer’ in the brain tracks sleep — and predicts awakening
A fever dream of jellies and slugs
How to prevent AI from harming mathematics
Phase-homogeneous mixed halide perovskites for stable tandem photovoltaics
Pyridoxal photoenzymes for asymmetric radical–radical cross-couplings
Systemic and local chronic inflammation and hormone disposition promote a tumor-permissive environment for breast cancer in older women
Researchers are building computers that run on brain organoids — but have neglected a major ethical issue
When should you treat a fever? Evolution holds the answer
The existential choice facing UK physics facilities: commercialize or close
Future of giant monkey research facility uncertain, even as sanctuary plan dropped
The Oregon National Primate Research Center could change its name and shift its focus to nonanimal studies
独家披露:一名女孩在中国基因编辑试验中死亡,此事从未对外公开
试验酿成灾难性悲剧后,受害者父母寻求问责,《科学》与 Retraction Watch 联合调查发现
Clear sighting of ‘wandering’ black hole reveals escapee from galaxy merger
Stripped-down behemoth promises new insights into how galaxies grow, astronomers say
A California aquifer may have crossed the point of no return
Satellite data reveal in unprecedented detail how groundwater reservoirs permanently lose their ability to store water
AI’s top startups are barely publishing their research
More than half of AI “unicorns” have never published a paper or preprint
Chinese university launches probe into girl’s gene-editing death
More than a year after failed clinical trial, Shanghai Jiao Tong University School of Medicine promises “serious action”
Your AI calorie-tracking app may be off by 345 calories
Popular AI-powered food apps may make calorie counting easier, but they may also leave out a surprisingly large part of the meal. Four apps underestimated calories and fat by about one-third when tested against carefully prepared meals. High-fat ketogenic dishes appeared to cause the most trouble, while carbohydrates were measured more consistently.
CRISPR makes prostate cancer vulnerable to immunotherapy
Scientists used CRISPR to make prostate cancer cells easier for the immune system to detect and destroy. The experimental treatment dramatically improved the effects of immunotherapy in mice and may offer hope for other hard-to-treat tumors.
Why losing the wrong fat can trigger diabetes
Scientists discovered that damaged fat cells can become inflamed, lose their ability to store lipids, and eventually vanish, disrupting the body’s metabolism. The findings show that diabetes can result not only from excess fat, but also from losing the healthy fat tissue the body needs.