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A single gene-editing treatment could someday protect against heart disease, high cholesterol, and other common conditions for decades, potentially replacing lifelong medications. But scientists warn that permanently altering genes introduces risks that could take years to emerge, making long-term safety a critical challenge.

Astronomers mourn telescope that supercharged study of cosmic explosions

Scientists have developed a promising new cancer-fighting strategy that uses carbon monoxide naturally produced by tumor cells to manufacture powerful drugs inside the cancer cells themselves. Early laboratory experiments suggest the technique could selectively attack cancer while sparing healthy cells, potentially paving the way for safer chemotherapy alternatives.

Anthropic used its Claude AI to show bacteria and viruses also likely make the odd structures, suggesting an ancient origin

Research advocates welcome Democrats taking Congress but must still deal with Trump

Ancient DNA sheds light on history of modern languages such as Welsh and Gaelic

Science investigation reveals firms have amassed tens of millions of hours of brain wave data from neurotech headbands, and face few constraints in using it

As prospectors struggle, a new French borehole hints at potential of extracting gas from groundwater

A new study suggests that ultra-processed foods may influence children's developing brains in ways that encourage weight gain. Researchers from USC studied 46 children ages 7 to 10 and found that those who ate more ultra-processed foods showed stronger activity in the brain's reward system when viewing tempting foods like cookies and French fries. These heightened brain responses were linked to greater increases in body fat and body mass index (BMI) one year later, suggesting that the brain's sensitivity to food cues may help explain why ultra-processed diets are associated with obesity.

A surprising new discovery suggests that fear may cause the brain to blur the line between danger and safety rather than distinguish them more clearly. By observing brain activity in mice using augmented reality, scientists found that memories of threatening and harmless environments began to overlap, potentially allowing faster responses to danger. This "better safe than sorry" survival mechanism could help explain why people with anxiety or PTSD sometimes experience intense fear in completely safe situations.

Scientists have uncovered an unexpected connection between inflammation during pregnancy, placental damage, and autism-like traits in male mice, while females appeared naturally protected. The discovery could help explain why autism is diagnosed more frequently in boys and reveal new opportunities for early intervention.

Eating an avocado and a cup of mango every day may provide surprising benefits for heart health, according to a new study involving adults with prediabetes. After just eight weeks, participants experienced significant improvements in blood vessel function and diastolic blood pressure, particularly among men. These benefits occurred without weight gain or changes in calorie intake, suggesting that the nutrient-rich combination could support cardiovascular health through a simple dietary adjustment.

A massive new study reveals that intelligence plays a surprisingly limited role in children's reading success, while visual processing showed no meaningful connection at all. Instead, the strongest predictors are sound recognition, vocabulary, and background knowledge, offering new clues about how to help struggling readers.

Mark Dybul contends the group can finally help countries control malaria, TB, and HIV

More than €55 billion from EU fund has gone to research and innovation, but researchers worry those investments will not be sustained

Vagus nerve stimulation has shown promising neuroprotective and anti-inflammatory effects in progressive neurodegenerative disorders such as Parkinson's disease. However, its invasive nature introduces procedural and device-related risks. Here we introduce a magnetoelectric particulate system for oral delivery and non-invasive vagus nerve stimulation through the gut. The system comprises a magneto-responsive nickel ferrite core and a piezoelectric barium titanate shell, conjugated with capsaicin...

An age-related neurovascular impairment in nitric oxide (NO)-mediated vasodilation and reciprocal Piezo1-dependent vascular vasoconstriction may precede the accumulation of soluble brain proteins such as amyloid-β (Aβ) and disruption of brain fluid homeostasis in Alzheimer's disease (AD). Preclinical studies suggest that restoring these pathways can enhance neurofluid transport and improve cognitive outcomes. In this study (EudraCT 2021-000625-27), we investigated the effects of sublingual NO...

Aging is characterized by progressive physiological decline and increased susceptibility to age-related diseases. Conventional rodent models have contributed significantly to our understanding of aging, yet their translational relevance is limited by substantial evolutionary divergence from humans. Here, we introduce the tree shrew (Tupaia belangeri chinensis) as a novel and biologically relevant model organism for aging research. In vitro, we induced cellular senescence in tree shrew...

CONCLUSIONS: Risk factors for PSO differ substantially by sex and age. These findings support targeted prevention strategies: weight control in men, nutritional and inflammatory monitoring in women, metabolic management in younger-old adults, and weight control in the oldest-old.

CONCLUSION: Both LL-BFR and W-BFR may improve lower-limb muscle strength and physical performance in older adults, particularly when compared with no intervention or conventional walking. Lower-limb BFR training may therefore have a potential role in sarcopenia prevention and early management in aging populations, especially for individuals who are unable to tolerate high mechanical loads.