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Science, Ahead of Print.

Some of the attention patterns that make ADHD challenging may also help spark creativity by allowing the brain to explore more ideas and unexpected connections. Researchers think creative activities could potentially channel this “defocused attention” while helping strengthen the brain systems involved in focus and self-control.

Sitting for long, uninterrupted stretches may carry greater health risks than sitting the same amount of time in shorter bouts. Researchers found that each extra hour of prolonged sedentary behavior was associated with a 9% higher risk of cancer death. Breaking up sitting with movement showed the opposite pattern, while replacing an hour of prolonged sitting with light activity was linked to a 12% lower risk.

Regulators crack down on stories that were too positive about drugs that target GLP-1

Research in mice finds that psilocybin protects against nerve damage and sensitivity caused by common cancer drugs

Amid a shortage of human reviewers, tests indicate AI can assist—but is not a savior

New approach that induces patients to make their own CAR-T cells could be faster and cheaper than existing methods

The indefinite move to Europe was a response to travel and safety concerns for winners

“Broken heart syndrome” can mimic a heart attack so closely that patients often need invasive testing to tell the difference. Researchers have now developed the BioTAK score, which combines biological sex with blood biomarkers to identify the condition before cardiac catheterization. In a validation study of nearly 1,800 patients, it correctly classified almost 90% of participants.

Persistent financial hardship in early and middle adulthood was linked to poorer thinking skills by the 50s and more signs of brain aging later in life. Researchers say years of chronic stress and financial worry may gradually take a toll on the brain.

Brain changes associated with Alzheimer’s may begin at least seven years before amyloid plaques become detectable with current PET scans. Researchers uncovered the signal by tracking healthy older adults with repeated brain imaging over nearly 20 years. The discovery could help scientists identify Alzheimer’s earlier and suggests that important disease processes may start before visible plaque buildup.

CONCLUSION: Consistent with the broader tele-neuropsychology literature, direct-to-home assessment is feasible and acceptable in older adults, with evidence indicating comparable test reliability to clinic standards. Embracing this practice model may promote greater support and access to neuropsychological assessment for older adults.

The absence of periodic atomic arrangement makes it difficult to detect microscopic defects in metallic glasses, yet their roles in macroscopic shape change are prominent. Motivated by probing defects mechanically, we perform stepwise tensile creep at ambient temperature on as-spun metallic-glass ribbons that show structural anisotropy in selected area electron diffraction. The main discovery is a non-linear strain response in which the segmentally added stress causes the creep strain to...

Parkinson's disease (PD) is a neurodegenerative disorder involving a neuroinflammatory response, the cause of which remains unclear. Transposable elements (TEs) have been linked to inflammation, but their potential role in PD remains unexplored. Using bulk- and single-nuclei RNA-seq of postmortem brain tissue from four brain regions, we studied TE transcription and its correlation with PD neuroinflammation. Over a thousand TEs, including LINE-1 s and ERVs, were expressed in a cell type- and...