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Can you terraform Mars? Try <i>Nature</i>’s game
China’s LineShine just topped the global supercomputer ranking: what you need to know
US funding uncertainties threaten to sink key global oceanography projects
Oo oo, ha ha: why humans and great apes giggle alike when tickled
Base editing reveals an essential role for NANOG in human embryogenesis
Ligand-enabled distal desaturative lactonization of aliphatic acids
Publisher Correction: In situ nanocrystal confinement for efficient blue perovskite LEDs
How long-term dietary cholesterol can slow down its own clearance by liver cells
The origin, history, and resistance architecture of an invasive urban malaria mosquito in Africa
Science, Ahead of Print.
Constraining an exoplanet’s magnetic field using star-planet interactions
Science, Ahead of Print.
Cyclic sealing and drainage on an oceanic transform fault
Science, Ahead of Print.
Osteopenia is silently weakening bones in millions of people
Osteopenia is a common but often overlooked condition that causes bones to become less dense and more fragile. Because it develops silently, many people only discover they have it after a fracture or bone scan. Aging, menopause, poor diet, and inactivity can all contribute to bone loss. Fortunately, exercise, adequate calcium and vitamin D, and other healthy habits can slow or even partially reverse the decline.
As better chatbots get harder to build, AI turns to simulated worlds
In pursuit of human-level intelligence, researchers are developing agents that learn by acting in virtual environments rather than simply absorbing more text
The universe may be hiding conscious minds stranger than we can imagine
What if consciousness isn’t limited to brains like ours? Philosophers Eric Schwitzgebel and Jeremy Pober argue that consciousness could arise in many different forms of life, even in beings built from radically different materials than those found on Earth. Drawing on the vastness of the universe and the likely existence of countless alien civilizations, they suggest it would be surprisingly Earth-centric to assume that only Earth-like biology can support conscious experience.
Scientists discover ancient brain cells that help block distractions
Scientists have discovered a tiny group of neurons in an ancient brain region that acts like a built-in focus filter, helping the brain ignore distractions and zero in on what matters most. When researchers temporarily switched off these neurons in mice, the animals became unusually distractible—similar to what is seen in ADHD—but regained normal focus as soon as the neurons were reactivated.
Scientists discover hidden “footprints of death” that may help viruses spread
Scientists have uncovered a surprising new twist in what happens when cells die. As dying cells break apart, they leave behind tiny “footprints of death” packed with newly discovered particles that help guide the immune system to clean up the remains. But researchers found that influenza viruses can exploit this process, hiding inside these microscopic packages and potentially using them to spread to nearby cells.
Retraction questions claim that cancer therapy works better in morning
Investigation finds problems in a key clinical trial that critics said was too good to be true
Why were mysterious ancient humans found in an African cave all female?
Analysis of fossil proteins deepens mystery of the enigmatic Homo naledi
Explorative investigation on effects of multi-day neurofeedback with implanted electrodes in patients with Parkinson's disease
Neurofeedback, which consists of recording and visualizing neural activity in real-time, is a method currently being investigated as a supplementary treatment for Parkinson's disease (PD). By using implanted deep brain stimulation (DBS) electrodes with interleaved sensing capability, previous studies have demonstrated the efficacy of neurofeedback based on beta oscillations in the basal ganglia. Herein, for the first time, we explored short-term neurofeedback ability over the course of multiple...
Targeting of RhoA-ROCK pathway activators and linked molecular signaling in Alzheimer's disease: The paving dawn for future therapy
Rho-associated protein kinase (ROCK) is a serine/threonine kinase that plays a central role in regulating cellular processes, including growth, proliferation, survival, and migration. ROCK exists as two isoforms, ROCK1 and ROCK2, which function as the principal downstream effectors of Rho GTPases. Activation of the RhoA-ROCK signaling pathway is induced by a variety of extracellular stimuli, including angiotensin II (Ang II), platelet-derived growth factor (PDGF), integrins, and vascular...