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mRNA vaccine from Merck and Moderna slashes risk of melanoma’s return, but why remains unclear

Deaths can be prevented by regulating when wind turbines operate, scientists say

Jumping spiders enter a REM-like state, darting their eyes and twitching their legs. What’s happening beyond that remains unclear

A simple liquid painted onto teeth in seconds can stop cavities without drilling, injections, or anesthesia, according to a major clinical trial involving young children. The inexpensive treatment could spare thousands of children painful dental procedures and surgery while paving the way for broader FDA-approved use.

Missing blood pressure medication could mean losing much of its protection against heart attacks and strokes, according to an analysis of more than 91,000 people. Patients who consistently took their medication experienced an 11% reduction in major cardiovascular events, while those who missed too many doses saw little or no measurable benefit.

A major new study reveals that drinking just two alcoholic beverages a day is associated with a 1 in 25 lifetime risk of death from alcohol-related causes, challenging the idea that moderate drinking is harmless. Researchers also found no significant overall health benefits from alcohol, with risks rising as consumption increases.

Scientists have discovered how pancreatic cancer cells continually reshape their genetic makeup to become more aggressive, spread, and evade treatment. In laboratory experiments, blocking a key gene reversed some of these dangerous changes, revealing a potential new way to fight the deadly disease.

A common, inexpensive medication could hold an unexpected clue to preventing dementia. Researchers found that older adults with a specific genetic profile had a 70% lower relative risk of dementia when taking low-dose aspirin, even though previous studies found no overall protective effect. The discovery suggests that genetics could help explain why some people benefit while others do not.

Aging is accompanied by a progressive decline in immune function, increasing susceptibility to infections, cancer, and poorer treatment outcomes. The diversity of the T cell receptor (TCR) repertoire, reflecting the capacity to recognize diverse antigens, is known to decline with age. However, how intrinsic and extrinsic factors jointly shape TCR diversity and its rate of decline, as well as the extent to which this diversity influences clinical outcomes in cancer, remain poorly characterized....

Mitochondria are central regulators of cellular metabolism, integrating energy production, redox balance, and signaling pathways that shape aging trajectories. If mitochondrial organization contributes to lifespan divergence, exceptionally long-lived species should exhibit distinctive metabolic signatures reflecting adaptations promoting long-term cellular maintenance. Comparative approaches across species with extreme lifespan variation provide a powerful framework for identifying potential...

Ginsenoside Rg1, the main active component of Panax ginseng, has been shown to improve mitochondrial function and delay cell aging by regulating chaperone-mediated mitophagy. However, how Rg1 works in Caenorhabditis elegans is still unclear. In this study, C. elegans was used as a model to study how Rg1 regulates autophagy and mitochondrial function, and to understand its anti-aging mechanism. The results showed that Rg1 treatment significantly kept cells alive and maintained muscle shape in...

For nearly a century, people in distant parts of the world have reported a bizarre experience after eating certain wild mushrooms: seeing dozens or even hundreds of tiny, colorful humans moving through the real world. Now, scientists have identified a mushroom species, Lanmaoa asiatica, responsible for these extraordinary hallucinations in China and the Philippines.