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Social participation and subjective well-being among older adults: item-level evidence and screening potential in an East Asian aging society
CONCLUSION: Higher social participation is strongly associated with better subjective well-being in older adults, particularly through relational and health-oriented activities. Social participation scores may serve as a useful community-based indicator for detecting low well-being. Culturally sensitive interventions that promote meaningful, voluntary, and inclusive participation-alongside structural supports such as transportation and social prescribing-may help enhance psychological well-being...
Patient-reported measures of physical activity level for older adults in the home care setting: a systematic review and assessment of psychometric properties
CONCLUSIONS: CHAMPS, PASE, and LAPAQ showed the most acceptable psychometric properties. Most PROMs had limited responsiveness and inconsistencies. Implementation should focus on robust PROMs, while research should enhance measurement quality, validate tools in home care settings, and standardize measurement methods.
Determinants of medical students' perceptions of older people: a cross-sectional study
CONCLUSIONS: Medical students mostly demonstrated positive attitudes towards older people, particularly in terms of respect and willingness to provide support. Regular contact with older people and appropriately designed gerontological education may contribute to more positive attitudes towards older adults and help counteract ageism among future healthcare professionals.
Age-Associated Senescence of Decidual Macrophages: A Key Mediator of Adverse Pregnancy Outcomes in Advanced Maternal Age
Senescence of immune cells can drive senescence of solid organs, and reversing immune cell senescence ameliorates organismal senescence phenotypes. As the second largest subset of decidual immune cells, macrophages play a critical role in pregnancy. However, whether decidual macrophages (DM) exhibit senescence in advanced maternal age (AMA) pregnancies (≥ 35 years old) and their involvement in AMA-related adverse outcomes remain undefined. This study elucidates the phenotypic and functional...
Daily briefing: ‘Cyborg’ cockroaches breathe underwater with printed suit
Neutrino’s nursery found: the ‘Shadow Blaster’
Modulating IL-11-dependent matrix stiffness to delay ovarian aging
Mapping the network architecture of aging to identify repurposable drug candidates for longevity
Targeting interleukin-11 to slow ovarian aging
Author Correction: Synthesis of enantioenriched atropisomers by biocatalytic deracemization
Electrodeposited self-assembled molecules for perovskite photovoltaics
Incoming US science academy chief vows to ‘double down’ on research
Can you actually do a nine-to-five PhD? <i>Nature</i> readers weigh in
A CDK1 phospho-switch reprograms TRAIP to unload replisomes in mitosis
Science, Ahead of Print.
TTF2 processes sites of incomplete DNA replication during mitosis via sister-chromatid exchanges
Science, Ahead of Print.
Manipulation of protein translation and stem cell self-renewal by CRISPR activation of rRNA transcription
Science, Ahead of Print.
Hierarchical sensory processing in zebrafish thalamocortical-like circuits
Science, Ahead of Print.
Being a taller tree doesn’t doom you to drought after all
New study challenges idea that tall trees’ hydraulics make them more vulnerable to dry conditions
Major Ukraine research center damaged in Russian strikes
Damage to century-old Palladin Institute marks “disaster for biological science in Ukraine”
First-ever treatment trial for Ebola Bundibugyo kicks off in the Congo
Scientists will test an antiviral drug and an antibody cocktail designed to tame the burgeoning outbreak