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New study quantifies the “blockbuster effect”—and argues it could help today’s threatened species

Critics question baffling genetic data from prolific infectious diseases group

Despite a healthy majority, Democrats face limits on what they can achieve

Even when bad cholesterol is brought down to healthy levels, some people remain at risk of heart attacks, and scientists may have discovered why. Researchers identified two types of fat-carrying particles that appear to promote inflammation and damage blood vessels through mechanisms beyond cholesterol buildup.

A surprising discovery suggests that some early signs of Alzheimer’s disease may begin outside the brain. Using miniature laboratory systems made from human cells, scientists found that genetic mutations associated with inherited Alzheimer’s can disrupt nerve-to-muscle connections without any involvement from the brain or spinal cord. This could help explain why some patients experience changes in balance, walking, and coordination long before memory problems develop.

Scientists have uncovered a hidden gut-to-brain dopamine pathway that helps explain why bitter coffee and other initially unpleasant flavors can become favorites over time. The discovery reveals how the brain learns to crave certain foods and could eventually lead to new ways of reshaping eating habits and food preferences.