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‘Immortal’ stars have an elixir of youth: dark matter
Biggest trial of four-day work week finds workers are happier and feel just as productive
Solving aviation’s climate-action conundrum
Scientific jargon can be ‘satisfying’ — but misleading
‘We dissent’: NASA staff declare opposition to Trump cuts
How AI can deepen inequities for non-native English speakers in science
‘We have less than ten minutes’: how I communicate with spacecraft from the ground
AI, bounties and culture change, how scientists are taking on errors
Budget brainwaves: low-cost system collects brain data outside the lab
Meet the biotech-company founders driven by their child’s rare disease
Why evaluating the impact of AI needs to start now
Should we treat rivers as living things?
Octopuses fall for the ‘rubber arm’ illusion, just like us
Experiment shows octopuses feel body ownership, a trait previously seen only in mammals
Insect X-Men: Helmets help these odd bugs sense electric fields
Ability may help treehoppers distinguish friend from foe
Storing hydrogen in oil-like liquid could allow easy transport in trucks and ships
Cheap catalyst could improve global access to costly green fuel
Betelgeuse’s long-predicted stellar companion may have been found at last
Small star could crash into red supergiant in the next 10,000 years
Enhanced focality and intensity in deep brain targeting: In silico study on multi-channel temporal interference stimulation for Parkinson's disease
This study introduces a novel multi-channel temporal interference stimulation (M-TIS) paradigm and rigorously evaluates its capacity to non-invasively target the globus pallidus internus (GPi), a pivotal region in Parkinson's disease (PD) treatment. Employing realistic human head models derived from MRI data and sophisticated finite element modeling, we demonstrate that M-TIS achieves significantly enhanced stimulation intensity and focality within the GPi compared to conventional single-channel...
Smoking Promotes AT2 Cell Senescence and Exacerbates Pulmonary Fibrosis by Downregulating POT1 via Integratively Inducing CpG Methylation and MECP2-Mediated FOXP2 Transcriptional Binding Inhibition
Smoking is one of the most recognized risk factors for pulmonary fibrosis (PF). However, the underlying mechanism is not well understood. This study reveals smoking increases the risk of developing idiopathic PF (IPF) and that smoked IPF patients exhibit higher levels of senescence markers than non-smoker IPF patients. Moreover, smoking enhances bleomycin (Bleo)-induced PF, along with obvious senescence of type II alveolar (AT2) cells. RNA-seq assay identifies cigarette downregulates protection...
How your research can survive a US federal grant termination
Amyloid and tau pathologies cross-talk to promote Alzheimeŕs disease: novel mechanistic insights
Aging-related declines in energy metabolism represent a key risk factor for the development of amyloid pathology, the earliest hallmark of Alzheimer's disease. Aging also contributes to the emergence of the second major hallmark, tau pathology, whose propagation is facilitated by pre-existing amyloid accumulation. The overlap of amyloid and tau pathologies ultimately leads to neurodegeneration and the onset of Alzheimer's disease-the most prevalent form of dementia. Recent findings underscore a...