Nature Aging
An International Working Group viewpoint on stratifying risk and prevention of the clinical expression of Alzheimer’s disease
Boosting astrocytic NAD<sup>+</sup> against tauopathy
Aging by the clock and yet without a program
A phase-of-care approach to improve geriatric fracture care
Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems
A blood DNA methylation test reveals how quickly each organ system is aging
Jeremy D. Walston (1961–2025)
Are we getting closer to understanding why we age?
Mitochondria-associated condensates maintain mitochondrial homeostasis and promote lifespan
Senescent-like border-associated macrophages regulate cognitive aging via migrasome-mediated induction of paracrine senescence in microglia
Plasma proteomic associations with Alzheimer’s disease endophenotypes
Population aging in Japan offers a warning and a template for action
Emerging strategies, applications and challenges of targeting NAD<sup>+</sup> in the clinic
The X-Age Project to construct a Chinese aging clock
Towards a personalized approach in senolytic trials
COVID-19 accelerates vascular aging
A blood-based DNA damage signature in patients with Parkinson’s disease is associated with disease progression
The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation
Midlife hearing loss and dementia risk
Nerve-associated macrophages control adipose homeostasis across lifespan and restrain age-related inflammation
How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
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