Nature Aging
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle
Therapeutic targeting of the conserved region within the low-complexity domain of TDP-43 is neuroprotective and extends survival in amyotrophic lateral sclerosis mice
Age-related molecular changes that are exercise independent
Modulating IL-11-dependent matrix stiffness to delay ovarian aging
Mapping the network architecture of aging to identify repurposable drug candidates for longevity
Targeting interleukin-11 to slow ovarian aging
Therapeutic inhibition of telomeric DNA damage response rescues hematopoietic dysfunction driven by telomere shortening and aging
Inhibition of telomere damage signaling restores hematopoiesis and immune function
Associations of proteomic age clocks with lifestyle risk factors, incident chronic diseases and mortality in two European cohorts
Meta-analysis of DNA methylation aging signatures in 17 human tissues
Network-driven discovery of repurposable drugs targeting hallmarks of aging
The blood metabolome of brain health in midlife and influences of genes, microbiome and exposome
Hierarchical endpoints and win statistics for geromedicine trials
Epigenetic clocks as quantitative readouts of epigenetic drift
Circulating metabolites at the crossroads of lifestyle and brain health
Are GLP-1 receptor agonists gerotherapeutics or just treatments for obesity?
Reaching for the cure as progeria research comes of age at the 12th international scientific workshop
Aging disrupts spatiotemporal coordination in the cycling murine ovary
Profiling the molecular and physiological effects of senolytic treatment on aged mice identifies immune, fibrotic and metabolic remodeling
Nuclear export of R-loop by the DDX1 and XPO1 complex promotes senescence-associated secretory phenotype and inflammaging
How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
Subscribe to Nature Aging feed