Nature Aging
A need for pragmatism in preclinical aging and longevity research
Two modes of aging to explain why lifespans differ across species
Author Correction: Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia
An open competition for biomarkers of aging
Single-nucleus interrogation of primate small intestinal aging reveals NCoR1 decline as a conserved feature that is reversed by metformin
A damage accumulation model identifies distinct aging regimes across species
Systematic review assesses link between physical activity and epigenetic age
Time-restricted feeding puts mouse healthspan on the clock
Time-restricted feeding extends healthspan in both sexes and lifespan in male C57BL/6 J mice
DREAM repressive activity links somatic mutation, lifespan and disease
Questions of the future in aging and longevity research at the GIMM Festival
Proteomic aging clocks in epidemiological studies: advances, applications and prospects
From whole-body to organ-specific biological age clocks
Peroxisomes orchestrate metabolic flexibility and longevity via an interorganelle cascade
A unifying model of stem cell dynamics explains age-related methylation patterns across mammals
Predicting categorical and continuous Alzheimer’s disease outcomes from a single MRI scan
Proteomic signatures of the <i>APOE</i> ε<i>4</i> and <i>APOE</i> ε<i>2</i> genetic variants and Alzheimer’s disease
Glutamine-driven reductive TCA cycle metabolism supports aged muscle stem cell function via de novo lipogenesis
Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer’s disease pathology
Urinary detection of therapy-induced senescence and fibrosis using an injectable albumin-based nanoprobe
How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
Subscribe to Nature Aging feed