Nature Aging
Time-restricted feeding puts mouse healthspan on the clock
Time-restricted feeding extends healthspan in both sexes and lifespan in male C57BL/6 J mice
DREAM repressive activity links somatic mutation, lifespan and disease
Questions of the future in aging and longevity research at the GIMM Festival
Proteomic aging clocks in epidemiological studies: advances, applications and prospects
From whole-body to organ-specific biological age clocks
Peroxisomes orchestrate metabolic flexibility and longevity via an interorganelle cascade
A unifying model of stem cell dynamics explains age-related methylation patterns across mammals
Predicting categorical and continuous Alzheimer’s disease outcomes from a single MRI scan
Proteomic signatures of the <i>APOE</i> ε<i>4</i> and <i>APOE</i> ε<i>2</i> genetic variants and Alzheimer’s disease
Glutamine-driven reductive TCA cycle metabolism supports aged muscle stem cell function via de novo lipogenesis
Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer’s disease pathology
Urinary detection of therapy-induced senescence and fibrosis using an injectable albumin-based nanoprobe
Mirroring tissue senescence in human biofluids
Hypoxia-induced autophagic degradation of HIF-1α attenuates cellular aging and extends mammalian lifespan
Brain endothelial cell-derived extracellular vesicles (c-BEEVs) as a promising biomarker for brain vascular pathology and cognitive decline
Somatic variants in microglia-like cells linked to Alzheimer’s disease pathology
Tissue softness unlocks regeneration
The aging extracellular matrix as a missing link in senescent cell accumulation and persistence
Mitigating the Hawthorne effect in aging research
How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
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