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Proteomic Signatures of Epigenetic Age in African Green Monkey Cerebrospinal Fluid and Plasma
Strategies to slow the aging process or mitigate its consequences on health rely on the validation of minimally-invasive biomarkers of aging that can be used to track aging and test the effectiveness of antiaging interventions. Study of aging in a nonhuman primate species offers a robust translational approach to achieving these aims, avoiding wide differences in genetics and environmental exposures that confound human aging studies. As epigenetic age appears to predict biological aging,...
Tissue-Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched-Chain Amino Acids
Dietary protein is a key regulator of healthy aging in both mice and humans. In mice, reducing dietary levels of the branched-chain amino acids (BCAAs) recapitulates many of the benefits of a low protein diet; BCAA-restricted diets extend lifespan, reduce frailty, and improve metabolic health, while BCAA supplementation shortens lifespan, promotes obesity, and impairs glycemic control. Recently, high protein diets have been shown to promote cellular senescence, a hallmark of aging implicated in...
Epigenetic Age Monitoring in Professional Soccer Players for Tracking Recovery and the Effects of Strenuous Exercise
Elite sports have become increasingly professionalized and personalized, with soccer players facing a high number of games per season. This trend presents significant challenges in optimizing training for peak performance and requires rigorous monitoring of athletes to prevent overload and reduce injury risks. The emerging field of epigenetic clocks offers promising new pathways for developing useful biomarkers that enhance training management. This study investigates the effects of intense...
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How to detect consciousness in people, animals and maybe even AI
AI models are neglecting African languages — scientists want to change that
Africa needs to invest in science communication — here’s how
Can science address painters’ problems?
The Virtual Lab of AI agents designs new SARS-CoV-2 nanobodies
Serum amyloid P secreted by bone marrow adipocytes drives skeletal amyloidosis
How China’s bold talent recruitment has shaped science
Early universe’s ‘little red dots’ may be black hole stars
Puzzling objects spotted by NASA’s JWST telescope may be entirely new class of celestial entity
Giant virus with record-long tail discovered in Pacific Ocean
Infecting marine plankton, the pathogen may use its extreme appendage to enter host cells
Prevalence and risk factors of abuse among older adults registered with health centers in Southern Tehran: a population-based study
CONCLUSION: The high prevalence underscores the need for routine screening in health centers and caregiver education programs.
Why space foods aren't just for space
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