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What harmful microbes are lurking in the world’s 7 billion tonnes of plastic waste?
Support the Pact for the Future
The huge toll of PhDs on mental health: data reveal stark effects
Peer review by committee? New journal rethinks old model
AI to the rescue: how to enhance disaster early warnings with tech tools
Why the timing of climate assessments matters
Funders launch online resource to help researchers navigate narrative CVs
Jordan’s green-energy vision requires refinement
International action is needed now to save the Pantanal
How walkable is your city? Online tool shows how major centres measure up
US election has profound implications for science in Ukraine
Essential vector-disease resource faces shutdown without funding
Dealers need not apply: shipping plants for science in 1874
Silicon heterojunction back contact solar cells by laser patterning
Aged eggs improve within young follicles
Why Mount Everest is the world’s tallest mountain
A river’s new course may have given Mount Everest a ‘growth spurt’
Erosion and uplift added 15 to 50 meters to world’s tallest mountain, study suggests
Healthy Aging at Moderate Altitudes: Hypoxia and Hormesis
BACKGROUND: Aging is associated with cellular and tissue responses that collectively lead to functional and structural deterioration of tissues. Poor tissue oxygenation, or hypoxia, is involved in such responses and contributes to aging. Consequently, it could be speculated that living at higher altitude, and therefore in hypoxic conditions, accelerates aging. This assumption is indeed supported by evidence from populations residing at very high altitudes (>3,500 m). In contrast, accumulating...
Mild Behavioral Impairment and Quality of Life in Community Dwelling Older Adults
CONCLUSIONS: The study shows that MBI is associated with poorer QoL, independent of sex, on two QoL scales. We addressed depression/anxiety items in the EQ-5D as a potential confounder for the observed MBI-QoL association by conducting a sensitivity analysis that excluded those items from the EQ-5D total score and by employing a novel measure of QoL (QFS-5) that excludes psychiatric symptoms from measurement of QoL. Associations of MBI with the novel QFS-5 were similar to associations between...
Prenatal exposure to undernutrition is associated with a specific lipid profile predicting future brain aging
Prenatal adversity affects cognitive and brain aging. Both lipid and leptin concentrations may be involved. We investigated if prenatal undernutrition is associated with a specific blood lipid profile and/or leptin concentrations, and if these relate to cognitive function and brain aging. 801 plasma samples of members of the Dutch famine birth cohort were assessed for lipidomics and leptin at age 58. Cognitive performance was measured with a Stroop task at 58, and MRI-based BrainAGE was derived...