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Distributed quantum computing across an optical network link
Directly imaging the cooling flow in the Phoenix cluster
The genetic origin of the Indo-Europeans
Superfluid stiffness of twisted trilayer graphene superconductors
Crowds suck people into a vortex — surprising physicists
Crowd crush: Could fluid dynamics save lives?
Multi-omic profiling of sarcopenia identifies disrupted branched-chain amino acid catabolism as a causal mechanism and therapeutic target
Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging
Transdisciplinary links between societal inequality and brain structure and dynamics
Multiomics atlas reveals molecular and genetic drivers of human ovarian aging
Poke, twist, vibrate: a wearable device that delivers touch to the skin
Lineage tracing of stem cells decades after blood and bone-marrow transplantation
Future legal
Cancer outcomes predicted using AI-extracted data from clinical notes
Are the Internet and AI affecting our memory? What the science says
Top universities warned against unfair research partnerships on their doorstep
‘It’s tectonic’: U.S. foreign aid freeze deals a blow to research around the globe
Dismantling of USAID could disrupt clinical trials and wipe away U.S. “soft power” in developing countries, scientists warn
New complexity emerges in Earth’s ‘boring’ middle region
Planetary CT scans and lab experiments reveal layering and intricate flows in the mantle
Indonesia’s new capital could become a hot spot for infectious diseases
Scientists worry about potential surge of a rare malaria parasite and a host of mosquito-borne viruses
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer's disease progression
Activation of the NLRP3 inflammasome has been implicated in the pathogenesis of Alzheimer's disease (AD) via the release of IL-1β and ASC specks. However, whether NLRP3 is involved in pathways beyond this remained unknown. Here, we found that Aβ deposition in vivo directly triggered NLRP3 activation in APP/PS1 mice, which model many features of AD. Loss of NLRP3 increased glutamine- and glutamate-related metabolism and increased expression of microglial Slc1a3, which was associated with enhanced...