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Neurovascular decoupling and compensatory network recruitment during speech perception in aging: evidence from EEG-fNIRS
Age-related decline in speech perception is a prominent challenge in auditory aging, especially under noise conditions. However, how neural and neurovascular processes are jointly organized and coordinated across adulthood during speech perception remains incompletely characterized. This study employed simultaneous electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) to investigate neural activation, functional connectivity, and neurovascular coupling across youth (n =...
How novel is that research paper? Competition to quantify concept crowns winner
The automated tool could be used to help journals vet submissions
Characterization of the m(6)A Epitranscriptome in Fibroblast Senescence
A critical developmental process affecting aging and age-associated disease, cell senescence is characterized by persistent growth arrest and adaptive gene expression patterns. A common RNA modification, N6-methyladenosine (m⁶A), regulates gene expression profiles but its impact on senescence has not been studied globally. Here, we elucidated the m⁶A landscape in proliferating and senescent human fibroblasts using epitranscriptomic microarray and m⁶A-crosslinking and immunoprecipitation followed...
Daily briefing: Human embryo genomes precisely altered
Nuclear-fusion firm says plant will deliver electricity to grid — but big questions remain
AI is taking on antibiotic resistance — here’s how
Bots are scraping open data — how should researchers respond?
Why are so many young people getting cancer? What researchers do and don’t know
How AI is reshaping discovery in maths and physics
Fifty years since a simple equation described the chaos of biology
Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding
Distributed control circuits across a brain-and-cord connectome
GPR15-guided CD8<sup>+</sup> T regulatory cells control intestinal inflammation
Sustainability or dystopia? What past patterns tell us about where society is heading
NIH plans to cap number of grants a scientist can have at once
Agency is bringing back a version of a funding limit that was quickly abandoned nearly a decade ago
Leading supplier of research monkeys declares bankruptcy
Facing economic and regulatory pressures, Inotiv says it is seeking ways to continue operations
Dementia risk linked to nitrate in drinking water, study finds
A major long-term study of more than 54,000 adults found that where nitrate comes from may matter far more than how much you consume. People who got more nitrate from vegetables—roughly the amount in a cup of baby spinach a day—had a lower risk of developing dementia, while higher nitrate and nitrite intake from red meat, processed meat, and even drinking water was linked to a greater risk.
Doctors thought this kidney drug helped some patients. It may help millions more.
A trio of major studies found that finerenone may protect the kidneys and heart in far more people than previously thought. The drug significantly slowed kidney disease progression and reduced the risks of kidney failure, heart failure, cardiovascular death, and overall mortality. Researchers saw benefits not only in patients with diabetes but also in those with non-diabetic kidney disease, a group with limited treatment options.
How did so many theropod dinosaurs come to have tiny arms?
Shrunken forelimbs were likely a byproduct of large, powerful skulls—with one notable exception
An embryo editing ‘first’ is more complicated than headlines suggest
Scientists may have a better way to make gene-edited babies, but it’s still far from safe