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Distinct epigenetic ageing patterns are associated with heterogeneity in kidney function decline in type 2 diabetes
Biological ageing is a heterogeneous process that shapes susceptibility to chronic disease. However, whether ageing patterns diverge within clinically defined type 2 diabetes (T2D) subgroups remains unclear. We investigated whether epigenetic age acceleration (EAA) differs across T2D phenotypes and whether these patterns relate to subsequent renal vulnerability. We included 607 multi-ethnic Asians with recent-onset T2D previously classified into three clinically distinct subgroups: mild...
An AI can invent entirely new languages. But is it creative?
Researchers debate whether tool produces genuinely novel tongues, or simply spits out a remix
Scrawled signature names a Maya astronomer for the first time
The autograph accompanies formulas devised to sync calendars with planetary movement
Party pooper: grandparents’ COVID risk rose after grandchildren’s birthdays
Daily briefing: The rise of evidence-based medicine
First ‘true sugar’ molecule found in space — offering hints to life’s origins
Author Correction: OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours
Perovskite–organic tandem solar cells with a photo-transformable stabilizer
Spatial mapping and senolytic targeting of senescent and disease-associated microglia in aged mouse brain white matter
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This microbiologist endured a four-year court battle over COVID-19 tests
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The rise of evidence-based medicine and the ‘mavericks’ who championed it
How voluntary work can boost your career in science
Rights for rivers and ice cream for all: top reads for the summer holidays
Tall and small trees are equally vulnerable to drought
Scientists discover a hidden heart valve risk linked to gum disease
Researchers found that bacteria linked to gum disease may help drive the development of calcific aortic valve stenosis by triggering inflammation and calcium buildup in the heart valve. The early findings suggest that keeping gums healthy could play a role in reducing the risk of this serious heart condition.
Plan to turn major monkey research facility into sanctuary may be dead
Lack of federal funds may have forced Oregon university to drop idea of converting national primate center into science-free refuge
Where you live could shape your dementia risk, massive study finds
Researchers analyzing data from more than 214,000 people found that dementia risk factors differ widely across countries, challenging the idea of a one-size-fits-all prevention strategy. At the same time, they uncovered surprisingly consistent patterns that could help shape smarter, more targeted public health efforts.
As the Arctic warms, gray whale boom turns into a bust
Scientists point to changes that jeopardize the marine mammals’ critical feeding grounds