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Device-independent quantum key distribution over 100 km with single atoms

2 weeks 2 days ago
Science, Volume 391, Issue 6785, Page 592-597, February 2026.
Bo-Wei Lu, Chao-Wei Yang, Run-Qi Wang, Bo-Feng Gao, Yi-Zheng Zhen, Zhen-Gang Wang, Jia-Kai Shi, Zhong-Qi Ren, Thomas A. Hahn, Ernest Y.-Z. Tan, Xiu-Ping Xie, Ming-Yang Zheng, Xiao Jiang, Jun Zhang, Feihu Xu, Qiang Zhang, Xiao-Hui Bao, Jian-Wei Pan

Identification of an engram ensemble mediating memory forgetting in the dentate gyrus

2 weeks 2 days ago
How the memory engram is organized at the cell-assembly level to support not only encoding of learned information but also memory flexibility remains elusive. Here, we propose a novel engram model encoded by two orthogonal learning-recruited neuronal ensembles in the mouse dentate gyrus. Reactivation of the Fos-tagged ensemble promotes memory retrieval, whereas reactivation of the Npas4-dependent ensemble drives forgetting, with manipulation of the forgetting ensemble inversely shifting memory...
Shiqiang Hu

Indigenous gut microbes modulate neural cell state and neurodegenerative disease susceptibility

2 weeks 2 days ago
The native microbiome influences numerous host processes, including neurological function. However, its impacts on diverse brain cell types remain poorly understood. Here, we performed single-nucleus RNA sequencing on the hippocampus of wild-type, germ-free mice, revealing the microbiome-dependent transcriptional landscape across all major neural cell types. We found conserved impacts on key adaptive immune and neurodegenerative transcriptional pathways. Mono-colonization with select indigenous...
Lisa Blackmer-Raynolds