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MIT scientists find a hidden cancer risk of the keto diet

2 weeks 1 day ago
A ketogenic diet increased small-intestinal tumors in cancer-prone mice while reducing tumors in the colon, revealing a strikingly different response within neighboring parts of the gut. Researchers traced the increased risk not to ketones, but to the way intestinal stem cells processed the diet’s high levels of fat. That fat-burning activity pushed the cells to multiply more rapidly, potentially raising the chance of cancerous changes.

Scientists reveal what seven days of fasting does to the human body

2 weeks 1 day ago
Scientists found that prolonged fasting triggers major changes throughout the body, but many of the most interesting effects only appeared after about three days without food. The results suggest fasting may influence health in ways that go beyond weight loss and could eventually inspire treatments that mimic its effects.

Vagus Nerve Stimulation Could Help New Skills Stick

2 weeks 1 day ago
Stimulating the vagus nerve after practice helped mice develop stronger long-term motor learning, revealing a potentially important window when the brain is still locking in a new skill. The effect was linked to rhythmic changes in brain blood vessels, hinting that body-to-brain signals may help prepare the brain for lasting change.

Scientists discover a human brain gene that can jump through DNA

2 weeks 1 day ago
Scientists have discovered a human gene with a remarkable double life: it appears to play an important role in brain cells while still retaining the ability to jump around the genome. Called BC200, the gene evolved millions of years ago from a mobile piece of DNA known as a transposon, but unlike most genes that arose this way, it never lost its mobility. Researchers even found BC200 embedded inside a human poxvirus, suggesting it may have jumped from infected skin cells into the virus.

Decoding epithelial-mesenchymal transitions with multi-omics

2 weeks 1 day ago
Epithelial-mesenchymal transition (EMT) is a highly dynamic and plastic cellular programme essential for embryonic development, tissue repair and ageing, and it is co-opted in pathological conditions such as cancer and fibrosis. The continuum of intermediate states and pronounced cellular heterogeneity that characterize EMT have historically limited systematic investigation across regulatory layers, including the transcriptome, epigenome, proteome and metabolome. Recent advances in...
Nitin Narwade