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A minimally invasive treatment that blocks inflammation-driving blood vessels in the knee provided significant pain relief and improved function for osteoarthritis patients, with benefits lasting at least a year. The procedure was safe, highly successful, and could offer a new alternative for people seeking relief before considering knee replacement.

Scientists are beginning to explore a hidden world of thousands of food chemicals that go far beyond the nutrients listed on nutrition labels. This “nutritional dark matter” may hold the key to understanding disease risk, healthy aging, and why different diets affect people in dramatically different ways.

European Space Agency mission will trace the relics of ancient mergers and probe the dark matter shaping galaxy growth

Depression appears to change what children notice in the faces around them, but the effect depends on family history. Kids with a higher inherited risk became more focused on sadness, while lower-risk children lost some of their natural attention to happy expressions.

Diabetes and dementia appear to be closely intertwined, with each condition potentially influencing the other. Problems with insulin and glucose can affect the brain’s energy supply, increase inflammation, and damage blood vessels linked to memory loss. Researchers are also finding that some popular diabetes medications may lower dementia risk. These discoveries are opening new possibilities for protecting brain health as people age.

Science chats with a researcher whose team is using “timescapes” to understand how nonhumans experience the world