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Biological Aging Acceleration in Major Depressive Disorder: A Multi-Omics Analysis
Major depressive disorder (MDD) is linked to a higher risk of premature aging, but the mechanisms underlying this association remain unclear. Using data from two population cohorts (UK Biobank and Finnish Twin Cohort), we evaluate the relationship between systemic and organ-specific proteomic and epigenetic aging acceleration and MDD. A lifetime history of MDD was associated with accelerated proteomic aging at both systemic and organ-specific levels-including the brain-in both cohorts, with...
AI chatbots can persuade voters to change their minds
DeepSeek’s self-correcting AI model aces tough maths proofs
AI chatbots can sway voters with remarkable ease — is it time to worry?
China’s scientific clout is growing as US influence wanes: the data show how
Persuading voters using human–artificial intelligence dialogues
The United Nations Ocean Decade: A catalyst for international collaboration enhancing ocean monitoring and data
Science, Volume 390, Issue 6777, December 2025.
Erratum for the Research Article “Homogenized chlorine distribution for >27% power conversion efficiency in perovskite solar cells” by Z. Xiong et al.
Science, Volume 390, Issue 6777, December 2025.
Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance
Science, Volume 390, Issue 6777, December 2025.
The levers of political persuasion with conversational artificial intelligence
Science, Volume 390, Issue 6777, December 2025.
The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin
Science, Volume 390, Issue 6777, December 2025.
Cohesin drives chromatin scanning during the RAD51-mediated homology search
Science, Volume 390, Issue 6777, December 2025.
Cohesin guides homology search during DNA repair using loops and sister chromatid linkages
Science, Volume 390, Issue 6777, December 2025.
Multiscale structure of chromatin condensates explains phase separation and material properties
Science, Volume 390, Issue 6777, December 2025.
Aluminium is crucial to vaccines — and safe. Why are US advisers debating it?
Author Correction: Activity of caspase-8 determines plasticity between cell death pathways
In Science Journals
Science, Volume 390, Issue 6777, Page 1012-1014, December 2025.
Toward science-based conviction criteria to deter wildlife crime
Science, Volume 390, Issue 6777, Page 993-995, December 2025.
Putting the U in quantum
Science, Volume 390, Issue 6777, Page 978-982, December 2025.
Experimental treatments target the brain’s ‘plumbing’
Science, Volume 390, Issue 6777, Page 968-970, December 2025.