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Ferroptosis-driven inflammaging in age-associated degenerative disorders: Molecular mechanisms and therapeutic potential of natural products
Persistent low-grade inflammation, oxidative stress, cellular senescence, and disturbance of cellular homeostasis are all connected with ageing and can lead to the development of age-related diseases. Ferroptosis, an iron-dependent type of controlled cell death, has been linked to these processes more and more. It may represent a key connection between inflammation, oxidative damage, and tissue failure as people age. With a focus on neurodegenerative, cardiovascular, metabolic, pulmonary, and...
The relationship between health literacy and active and successful aging: a cross-sectional study of active aging service center
CONCLUSION: Health literacy is a key factor of active and successful ageing. To promote active ageing, older adults care centres should prioritise health literacy.
Oil wells could become mines for critical minerals
Engineered fluids could extract metals from fracked reservoirs, supplying materials for solar cells and electric vehicles
Daily briefing: The sky as you’ve never seen it — the month’s best science images
Can pancreatic cancer be stopped in its tracks? Radical tactic raises hopes
A black hole’s jets have a halo effect
Battle of the Anthropocene: allegations re-ignite row over proposed geological epoch
Gaze into the cosmos and through the eyes of a bee — September’s best science images
‘Vibe coding’ makes the dictionary: AI terms recognized by Merriam-Webster
Retraction Note: Ribosomal frameshifting in the <i>CCR5</i> mRNA is regulated by miRNAs and the NMD pathway
The ‘missed disease’ that affects 190 million: endometriosis drug shows early promise
Could quitting ultra-processed food boost your mental health?
People with depression who dramatically cut ultra-processed foods experienced notable improvements in their symptoms in a small preliminary study. Researchers suspect healthier eating may benefit the brain partly by reducing gut damage and chronic inflammation.
Snowball refrigeration of Earth’s crust mimics glacial erosion
Science, Ahead of Print.
Alzheimer’s risk gene APOE4 may have a reversible weakness
The Alzheimer’s risk gene APOE4 may actively damage brain blood vessels and sabotage the cellular systems that remove harmful proteins. Researchers were able to reverse some of these effects in experiments, revealing promising new targets for Alzheimer’s, Parkinson’s, and other neurodegenerative diseases.
Nazi Germany had no hope of making an atomic bomb, uranium cubes reveal
Experimental reactor needed much more uranium and heavy water than the country could muster
This common mistake can add nearly 7 points to your blood pressure reading
A common mistake during blood pressure checks could make readings appear substantially higher than they really are. Johns Hopkins researchers found that leaving the arm unsupported can raise systolic readings by about 6.5 mmHg, potentially affecting a hypertension diagnosis.
Menopause puts the brain at risk. Researchers are starting to learn why
Shifts in blood proteins could point to ways to fight menopause “brain fog” and prevent later dementia
Africa’s effort to make most of its own vaccines by 2040 faces significant headwinds
Companies striving to reduce continent’s reliance on foreign shots must overcome major financial and logistical challenges
Cannabis users were twice as likely to commit violence, review finds
A review of more than 265,000 people found that cannabis use was associated with higher rates of both committing violence and becoming a victim of it. The researchers say the link is significant but does not prove cannabis itself is the cause.
Mulberry may reshape gut bacteria and influence metabolism
Mulberry compounds may reshape the gut microbiome in ways that support intestinal health and metabolism, with some combinations showing especially strong effects in animal studies. However, the results vary depending on the plant part and processing method, and the benefits have yet to be confirmed in humans.