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Kratom poison center cases have surged 6,500% in the U.S.

2 weeks 1 day ago
Kratom use and serious health problems linked to it have risen dramatically across the United States over the past decade. Poison center reports jumped from just 19 cases in 2010 to more than 1,200 in 2023, while severe outcomes—including life-threatening complications, disability, and death—also climbed sharply. Researchers warn that kratom can trigger seizures, abnormal heart rhythms, liver damage, and breathing problems, with risks potentially increasing when it is combined with other drugs.

The bacteria that make cheese taste so good may also benefit your gut

2 weeks 2 days ago
Scientists studying three artisan British cheeses found that the microbes responsible for their distinctive flavors may also offer surprising benefits for gut health. As the cheeses matured, helpful bacteria transformed their aromas and textures while potentially producing compounds linked to reduced inflammation, cholesterol regulation, and appetite control.

Low-fat vegan diet helps people lose weight without eating less

2 weeks 2 days ago
A low-fat vegan diet may help people lose weight without counting calories, shrinking portions, or feeling constantly hungry. In a 16-week clinical trial, people eating mostly fruits, vegetables, grains, and legumes consumed about 357 fewer calories per day even though the total amount of food they ate barely changed.

Scientists uncover the hidden nerve network fueling breast cancer

2 weeks 2 days ago
Researchers have uncovered a surprising way triple-negative breast cancer may turn the body against itself. Tumors appear to recruit macrophages—immune cells normally involved in healing and fighting infection—and use them to release a protein called BDNF that draws nerves into the tumor. Those nerves may then help the cancer grow, resist treatment, and potentially spread.

Corisin induces proteostasis stress to drive epithelial injury and pulmonary fibrosis

2 weeks 2 days ago
Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disease lacking clarity on the mechanisms linking epithelial injury to fibrotic remodeling. Here, we identify the microbiota-derived corisin as a potent, multifaceted driver of epithelial injury and pulmonary fibrosis. Leveraging targeted DNA sequencing of bronchoalveolar lavage fluid, we provide the first sequence-based identification of corisin in IPF patients and show that functional depletion of native corisin from patient...
Hajime Fujimoto

Protein restriction and the hallmarks of aging: A coordinated physiological adaptive response?

2 weeks 2 days ago
Protein restriction extends lifespan across species and engages many hallmarks of aging. We propose that these diverse responses can be understood as components of a single coordinated physiological state. This response involves both cellular nutrient sensing and endocrine and neural coordination, with enhanced longevity emerging from this adaptive response.
Sora Q Kim