Aggregator

An overview on the impact of viral pathogens on Alzheimer's disease

2 weeks 4 days ago
Alzheimer's disease (AD) is the most common type of dementia which affects over than 60 million cases worldwide with higher incidence in low and middle-income countries by 2030. Based on the multifactorial nature of AD different risk factors are linked to the condition considering the brain's β-amyloid plaques (Aβ) and neurofibrillary tangles (NFTs) as its primary hallmarks. Lately, viral photogenes specially after recent SARS-CoV-2 pandemic has gained a lot of attention in promoting the...
Melika AmeliMojarad

<em>Hydra</em> has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype

2 weeks 4 days ago
Growing evidence suggests that somatic mutations may be a major cause of the aging process. However, it remains to be tested whether the predictions of the theory also apply to species with longer life spans than humans. Hydra is a genus of freshwater polyps with remarkable regeneration abilities and a potentially unlimited life span under laboratory conditions. By genome sequencing of single cells and whole animals, we found that the mutation rates in Hydra's stem cells are even slightly higher...
Arne Sahm

An online driving decision aid for older drivers reduces ambivalence and regret about driving decisions: Randomized trial

2 weeks 4 days ago
CONCLUSIONS: In older drivers, the Healthwise® DDA reduced uncertainty and regret about driving decisions during longitudinal follow-up, without adversely affecting community mobility or crash risk. Use of DDAs in clinical and other settings may reduce the distress older adults often experience when making decisions about driving cessation.
Carolyn G DiGuiseppi