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In Other Journals
Science, Volume 390, Issue 6778, Page 1116-1117, December 2025.
The experiment I didn’t plan
Science, Volume 390, Issue 6778, Page 1182-1182, December 2025.
Infrared radiation is an ancient pollination signal
Science, Volume 390, Issue 6778, Page 1164-1170, December 2025.
Shapiro steps in strongly-interacting Fermi gases
Science, Volume 390, Issue 6778, Page 1125-1129, December 2025.
Substantial water retained early in Earth’s deep mantle
Science, Volume 390, Issue 6778, Page 1177-1180, December 2025.
Mesoporous optically clear heat insulators for sustainable building envelopes
Science, Volume 390, Issue 6778, Page 1171-1176, December 2025.
Global energy sector methane emissions estimated by using facility-level satellite observations
Science, Volume 390, Issue 6778, Page 1151-1155, December 2025.
Observation of Shapiro steps in an ultracold atomic Josephson junction
Science, Volume 390, Issue 6778, Page 1130-1133, December 2025.
Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes
Science, Volume 390, Issue 6778, Page 1156-1163, December 2025.
The statusocratic dilemma
Science, Volume 390, Issue 6778, Page 1108-1108, December 2025.
Dealing with distressing dreams
Science, Volume 390, Issue 6778, Page 1107-1107, December 2025.
ARF3-mediated auxin signaling is essential for sex determination in cucumber
Science, Volume 391, Issue 6780, Page 59-63, January 2026.
New antibiotics for gonorrhea could help beat back drug-resistant infections
Two treatments for the sexually transmitted disease are expected to become available soon
Congress imposes new security restrictions on U.S. researchers
But new defense bill drops or weakens some controversial proposals
Heat-seeking beetles drawn to plants that glow in infrared
Pollinators’ antennae act like thermal cameras to spot self-heating plants
NASA telescope will hunt down ‘city killer’ asteroids
With an infrared eye, NEO Surveyor will target dangerous space rocks glowing in the dark
Want to sway an election? Here’s how much fake online accounts cost
Systematic price monitoring sheds light on economics of online manipulation
Predictive modeling approaches for Alzheimer's disease diagnosis through neuroimaging techniques
Alzheimer's disease (AD) is one of the brain's neurodegenerative diseases. It is distinguished by a progressive mental, social, and behavioral deterioration. It affects the person's capacity, thinking, attention, reasoning, social behavior and functionality to achieve independence. The classical diagnosis process of AD consists of variety of neuroimaging scan approaches such as computerized tomography, magnetic resonance imaging and positron emission tomography. Classical cerebrospinal fluid...
Seed amplification of MSA alpha-synuclein aggregates preserves the biological and structural properties of brain-derived aggregates
Parkinson's disease (PD), Dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), are characterized by the misfolding and aggregation of alpha-synuclein (αSyn). Compelling evidence showed that αSyn aggregates exist as distinct conformational strains in different synucleinopathies. Recently, we reported that the αSyn Seed Amplification Assay (αSyn-SAA) can amplify and distinguish αSyn strains from PD and MSA. In this study, we investigate whether MSA-seeded, SAA-amplified αSyn fibrils...
Chimeras co-targeting antigens and FcγRIIb trigger degradation of extracellular soluble proteins and pathological aggregates
While the clinical utility of conventional antibody therapies is undeniable, their therapeutic potential is often constrained high antigen loads and the recycling of antibody-antigen complexes via neonatal Fc receptor (FcRn). Here, we present a platform, based on a design similar to bispecific antibodies, FcγRIIb-Targeting Chimeras (FcRTAC). These constructs recognise antigens with one arm and bind FcγRIIb with the other arm to harness the unique endocytic properties of FcγRIIb to direct the...