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Daily briefing: Iron-Age human bones were made into tools before interment
‘Every box has been opened’: London botanic gardens digitizes 7 million specimens
In the field — and in the lab — sometimes the simplest tool is best
At-home brain implant gives man with motor neuron disease his daily life back
Why people should work together to shape the economy
The latest benefit of obesity drugs: boosting testosterone and sperm quality
Nanocrystal-tailored recombination for all-perovskite tandem solar modules
A need for pragmatism in preclinical aging and longevity research
How AI is revealing the secret lives of animals from hummingbirds to pumas
Bones of Iron Age skeleton were whittled into tools
AI models have a troubling knack for discovering legal loopholes
AIs on their own found ways to exploit regulations and evade current safeguards
The secret behind smoother, better-tasting protein shakes
A new whey protein manufacturing technique could make protein shakes taste better and feel smoother in the mouth. Researchers traced unwanted bitterness to concentrated minerals and found a way to remove them without sacrificing the improved texture.
French physicist and media star loses doctorate after plagiarism investigation
University punishes Étienne Klein after investigation shows he plagiarized part of his Ph.D. thesis
Reversing prediabetes cuts risk of deadly heart problems by 58%
Bringing blood sugar levels back to normal may dramatically reduce the danger posed by prediabetes. Researchers found that people who reversed prediabetes cut their risk of cardiovascular death or hospitalization for heart failure by 58% and lowered their chances of major heart problems such as heart attacks and strokes by 42%. The benefits lasted for decades and were seen across large long-term studies in both the U.S. and China.
Trajectory of frailty among the older people in a community setting: A cohort study from the Shizuoka Kokuho Database
CONCLUSIONS: These findings highlight severe frailty as a late high-risk state and may inform age- and sex-specific frailty risk stratification and care planning.
Cellular senescence in ischemic stroke: Cell-type specificity, temporal dynamics, and response to therapeutic interventions
Increasing experimental and clinical evidence indicates activation of cellular programs resembling senescence and senescence-associated secretory phenotype signaling after stroke. However, a central challenge is definitional: in injured brain tissue, many senescence-associated features overlap with acute stress responses, transient cell-cycle perturbations, and reactive glial or vascular programs, complicating interpretation across models, time points, and cell types. Here, we synthesize the...
Nacre extract attenuates age-related functional and tissue alterations under post-onset intervention conditions in two murine aging models
Aging is accompanied by the accumulation of senescent cells and chronic low-grade inflammation, which together contribute to functional decline and tissue remodeling across organs. We previously reported that long-term nacre extract supplementation can delay age-related deterioration when initiated early; however, whether it can provide benefit under post-onset intervention conditions remains unclear. Here, we evaluated a water-soluble nacre extract derived from Pinctada fucata using (i)...
Awareness of active ageing and its association with quality of life among older adults in a tertiary care setting in Saudi Arabia: a cross-sectional study
CONCLUSIONS: The study findings showed a low level of awareness of the concept of active ageing among older adults in a tertiary care clinic in Saudi Arabia. Greater awareness of active ageing was positively associated with better quality of life among older adults, despite limited familiarity with the concept. These findings highlight the importance of integrating active ageing education into healthcare services and public health initiatives to support healthier and more fulfilling ageing...
Huge study hints at risks of switching from tobacco cigarettes to vapes
Scientists found a surprising problem with sugar-free diets
A surprising new study suggests that completely eliminating sugar may backfire. Mice on a sucrose-free low-fat diet showed worse blood sugar control, increased inflammation, disrupted gut bacteria, and signs of fatty liver compared with mice that consumed some sucrose. Researchers say the results highlight the importance of a balanced diet and a healthy gut microbiome rather than focusing solely on cutting out sugar.