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Some researchers get top tools for next to nothing—but others pay out of pocket or go without

Scientists have discovered that a drug originally developed for spinal cord injuries can tackle several key features of Alzheimer’s disease, including DNA damage and inflammation. Already tested for initial safety in humans, the experimental treatment could offer a faster path toward therapies that target the disease at its roots.

Potentially massive illicit trade could be endangering the animals and undermining Indigenous artists

A surprising discovery suggests that rejuvenating the liver could help protect against Alzheimer’s disease and heart disease. USC researchers found that an experimental drug restored aging liver cells in rats, cutting levels of an Alzheimer’s-linked protein in half and bringing bad cholesterol down to youthful levels. The treatment also revived a previously unknown communication system that helps liver cells remove harmful substances from the bloodstream.

A major 24-year study involving more than 8,200 adults suggests that excess body weight may accelerate brain aging, leading to faster declines in memory, concentration, and decision-making skills. The connection was particularly strong among people over 65, raising concerns about the long-term effects of obesity on brain health.

Scientists are calling for a major rethink of how we manage high blood pressure, suggesting that eating more potassium could be just as important as cutting back on salt. A new report finds that combining increased potassium intake with reduced sodium consumption may offer greater benefits for blood pressure control than sodium reduction alone.

Researchers have developed a remarkable new electronic implant that could transform type 2 diabetes treatment by lowering blood sugar without insulin or traditional drugs. The device uses a special electrically powered catalyst to convert excess glucose into a substance that the body eliminates through urine, potentially preventing unwanted energy from being stored as fat. In diabetic mice, the implant precisely controlled blood sugar and promoted weight loss.

In a surprising discovery, scientists found that certain diets associated with obesity can make cancer immunotherapy more effective in mice, challenging traditional assumptions about diet and cancer treatment. The findings suggest that the secret may lie in how food interacts with gut bacteria to strengthen the immune system's response to cancer.

There is an urgent global need for affordable, large-scale health screening to enhance preventive care in the ageing population. Using low-cost, non-invasive retinal photographs and leveraging large foundation models, we developed a deep learning-based biomarker, Retinal Mortality Equivalent (RetiME), that directly mapped retinal features to individual mortality risk. Trained on a European cohort and externally validated across three independent external cohorts spanning Southeast Asia, Eurasia...

Assessing and validating circulating biomarkers is essential for developing preclinical measures of biological aging in mice. However, comprehensive serum proteomics are limited by technical challenges and low sample volumes. Here we present a quantitative nanoparticle-based enrichment workflow coupled with data-independent acquisition mass spectrometry for deep proteomic profiling of low-volume mouse serum. This approach increased proteomic coverage by 3-6-fold with median coefficient of...