Aggregator

Science, Ahead of Print.

Science, Ahead of Print.

Girl’s death in China raises questions about the safety and cost of gene therapy, China’s biotech push, and scientific publishing practices

The 278 winners now face 9-month race to prove they deserve additional funding

Researchers have developed a fluoride-free gel that could help rebuild damaged tooth enamel, something the body cannot naturally replace once it is lost. Inspired by the proteins that guide enamel formation in infancy, the gel fills microscopic cracks and draws calcium and phosphate from saliva to grow a new mineral layer that closely matches healthy enamel.

Glassworms can hang out at pressures that would kill most humans, thanks to specialized air sacs

Parents want accountability after study went disastrously wrong, Science and Retraction Watch investigation reveals

A plant-derived compound reduced swelling, inflammation, and joint damage in rats with rheumatoid arthritis. It also helped rebalance immune activity and improve the way certain fats were processed in the body. Researchers say the findings could lead to a new approach for treating the disease.

Researchers found that specific brain circuits help decide which jobs bees perform as they age. When those circuits were switched off, older worker bees began caring for the queen again instead of carrying out their normal later-life duties. The findings reveal that a bee colony’s complex division of labor may be guided by neural switches hidden inside each bee’s brain.

Thousands of people will be screened for autoantibodies that help or hinder cancer

Colorectal cancer is now the leading cause of cancer death among people under 50, and cases in younger adults continue to rise. Warning signs can include persistent bowel changes, recurring rectal bleeding, dark or narrow stools, unexplained weight loss, and fatigue. These symptoms often have harmless causes, but they should not be dismissed, especially when they are new or ongoing. Early detection can greatly improve treatment outcomes.

Miniature brain models grown from patients’ cells revealed striking differences in how Alzheimer’s-related tissue responds to an antidepressant. The organoids and the particles they release could eventually guide more personalized treatments and provide new clues for diagnosing the disease.

Catfish melanomas are the first example of a transmissible cancer in fish, genetic studies reveal

CONCLUSIONS AND IMPLICATIONS: Among community-dwelling older adults, MRI-derived muscle quality deteriorated substantially faster than muscle quantity over 4 years and more closely paralleled declines in physical performance. These findings suggest that age-related muscle deterioration is driven primarily by qualitative degeneration rather than simple loss of muscle mass and support the use of imaging-based muscle quality measures as sensitive biomarkers of biological muscle aging.