Aggregator
Life-Prolonging Treatment Preferences and Their Association With Health Care Utilization and End-Of-Life Experiences in Older Adults
CONCLUSIONS: LPT preferences established in hypothetical scenarios were not associated with health care utilization, cost, or perceived quality of end-of-life. As LPT preferences should influence care, subsequent work, such as understanding preference measurement, real-world preference changes, or the limited opportunity for preferences to influence care, is warranted.
Realistic expectations for changes to average human lifespan in the near future
A recent publication presented the results of a survey given to longevity experts that attended the 2022 Systems Aging Gordon Research Conference. Corroborating results from a prior survey and broader discussions in the field, the authors found that there was little consensus on fundamental topics, including what causes aging. While this disagreement is not particularly surprising, the spread of answers to the following prompt was unexpected: "The average lifespan in developed countries will be...
Exploring the mediating role of telomere length in the association between physical activity and bone mineral density
CONCLUSION: Reduced physical activity and accelerated telomere attrition were related with BMD decline, and TL partially mediated the association. These findings suggest that enhancing physical activity could mitigate telomere shortening and promote bone health.
Regular glucosamine supplementation and risk of age-related chronic diseases: evidence from a propensity score-matched cohort study
CONCLUSIONS: Regular use of glucosamine was associated with a reduced risk of several age-related chronic diseases. Further studies are needed to confirm these findings and to clarify its potential role in supporting healthy aging.
Identifying latent classes of longitudinal change in picture naming in a population-based sample
Although cognitive changes may not become apparent until after age 65, many factors associated with late-life decline are already well-established in midlife. In particular, deficits in picture naming have been associated with early and accelerated cognitive change. A measure of picture vocabulary, requiring participants to name drawings of objects, was collected in 4 waves (each separated by 2 years) of the Understanding America Study, a nationally representative internet panel (mean follow-up...
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