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Long-term trends, age-period-cohort patterns, and future projections of incident stroke with comorbid hypertension and diabetes among older adults in Shenzhen, China: a population-based surveillance study
CONCLUSIONS: Among older adults in Shenzhen, the burden of stroke with comorbid hypertension and diabetes showed a long-term upward trajectory over the study period. Model-based projections suggested that the burden may increase from 2024 to 2033, particularly among males and older age groups. These findings provide population-level descriptive and projection evidence that may inform risk stratification and health service planning for ageing urban populations.
Life satisfaction in later life: the role of economic security, health, and religious belief among urban Iranian older adults
CONCLUSION: Life satisfaction in later life is associated with a multidimensional interplay of structural resources, health status, and existential orientation. Socioeconomic security and religious belief emerged as significant predictors of well-being, after controlling for health status. These findings highlight the importance of integrated policies addressing both material and psychosocial predictors of aging well.
Older adults' engagement with social prescribing to active ageing centres in Singapore: a qualitative study from public primary care
CONCLUSIONS: Uptake and sustained engagement with SP via AAC referral appeared to be shaped less by individual capability than by physical opportunity, social opportunity and motivation. Primary care providers are well placed to facilitate engagement by leveraging trusted patient relationships, while centre managers and policymakers should address structural barriers such as zoning restrictions, language mismatch and age-identity mismatch. These findings offer actionable insights to optimise the...
Latent profiles of the perceived age-friendliness of cities and communities in Colombia: relations to ageism experiences in later life
Age-friendly cities and communities (AFCC), together with initiatives to combat ageism, are recognised as two of the four action areas of the United Nations (UN) Decade of Healthy Ageing, have received global attention. However, there is a lack of understanding regarding the distinct experiences of older adults in their cities and communities, as well as the extent to which these experiences are linked to their perceptions of ageism. Using a sample of 398 older adults from four cities in...
Cardiovascular resilience in centenarians
Centenarians - individuals aged ≥100 years - provide a unique human model for understanding resilience to cardiovascular ageing. Although cardiovascular and metabolic diseases, including hypertension, heart failure, atrial fibrillation and chronic kidney disease, are common in centenarians, their onset is typically delayed relative to that in individuals aged 80-100 years. Centenarians characteristically have structural changes in the heart and vessels, including concentric left ventricular...
AI detects “invisible” signs of pancreatic cancer years before diagnosis
A powerful new AI system could help doctors detect pancreatic cancer years before it becomes visible on conventional scans. The technology, called REDMOD, identified hidden warning signs an average of 475 days before diagnosis and was nearly twice as sensitive as experienced radiologists. By spotting cancer-related changes at their earliest stages, it could dramatically improve the chances of successful treatment for one of the deadliest forms of cancer.
Daily briefing: <i>The Selfish Gene</i>, 50 years on
Brazil election: many scientists relieved as Lula wins surprise victory
Mentoring a lab colleague? Share your ‘CV of failures’ with them
<i>The Selfish Gene</i>, 50 years on — it’s time for an update
Evolutionary ‘game-changer’: weird armoured amphibian lived in ancient seas
Glimpsing archaeal microbes on the move
Can science make your dog live longer? Longevity craze comes to pets
Are salaries getting worse? Many scientists think so
Women might have invented language — but not alone
Nerve activity initiates autoimmune hair loss
Milestone cancer vaccine success leaves hard questions unanswered
mRNA vaccine from Merck and Moderna slashes risk of melanoma’s return, but why remains unclear
Wind turbines kill ‘shocking’ number of bats each year
Deaths can be prevented by regulating when wind turbines operate, scientists say
These spiders sleep like humans. But do they dream?
Jumping spiders enter a REM-like state, darting their eyes and twitching their legs. What’s happening beyond that remains unclear
A simple liquid can stop cavities without drilling, major study confirms
A simple liquid painted onto teeth in seconds can stop cavities without drilling, injections, or anesthesia, according to a major clinical trial involving young children. The inexpensive treatment could spare thousands of children painful dental procedures and surgery while paving the way for broader FDA-approved use.