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Determinants of malnutrition in older hospitalized patients: a prospective multicenter study with the DoMAP model
CONCLUSION: The DoMAP model provides a structured framework for capturing the diverse etiologies of malnutrition in older patients. This study emphasizes the multifactorial nature of malnutrition in hospitalized patients, with low intake and poor appetite emerging as predominant drivers.
Realization of a spin glass in a two-dimensional van der Waals material
Recent advances in van der Waals materials have sparked renewed interest in the impact of dimensionality on magnetic phase transitions. Although ordered magnetic phases have been demonstrated to survive in the two-dimensional (2D) limit, the quest for a spin glass with quenched magnetic disorder in lower dimensions has proven elusive. Here, we provide evidence of a spin glass emerging from randomly distributed Fe atoms in Fe(3)GeTe(2) (FGT). ac magnetic susceptibility displays a strong frequency...
Aging and the narrowing of scientific innovation
Aging researchers and the removal of retirement policies yield decreased disruptive innovation in science.
Association of Combined Lifestyle Behaviors With Healthspan in Older Adults
CONCLUSION: In healthy older adults, adherence to a healthy lifestyle was associated with a greater likelihood of surviving free from disability and dementia and was prospectively linked with a prolonged healthspan and a compression of morbidity, highlighting its potential importance in promoting healthy aging.
A conserved regulatory architecture stabilizes cellular senescence across distinct triggers in human fibroblasts
Cellular senescence arises through replicative exhaustion or acute stress, yet whether these distinct triggers share a reproducible transcriptional organization has remained unresolved. Seven public human fibroblast RNA-seq datasets were integrated across both trigger types, moving from differential expression through Gene Ontology and Reactome enrichment to protein-protein interaction network embedding within a single harmonized framework. Both triggers converged on concordant repression of...
Scientists find a way to stop dangerous belly fat as we age
Aging doesn’t just add fat—it redistributes it in risky ways, pushing more into the abdomen where it can harm health. Scientists found that testosterone plays a key role in this shift. In older women recovering from hip fractures, a testosterone gel combined with exercise helped prevent the usual rise in dangerous visceral fat. The result could point to a powerful new strategy for improving recovery and long-term health.
What to do with the passengers on the cruise ship hit by hantavirus?
Past studies of Andes virus offer scant evidence on transmission risks, and have sparked debate
Trafficked pangolins can be traced to their source by DNA — even to a specific forest
Daily briefing: A stunningly detailed map of the Universe and the month’s best science images
Early-career researchers do more ‘disruptive’ science than veterans
Erratum for the Report “The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine”
Science, Volume 392, Issue 6798, May 2026.
A molecule with half-Möbius topology
Science, Volume 392, Issue 6798, May 2026.
Rapid directed evolution guided by protein language models and epistatic interactions
Science, Volume 392, Issue 6798, May 2026.
Competitive reactivity drives size- and composition-focusing in multimetallic nanocrystals
Science, Volume 392, Issue 6798, May 2026.
Tuft dendrites in frontal motor cortex enable flexible learning
Science, Volume 392, Issue 6798, May 2026.
Intermetallic nanoassemblies potentiate systemic STING activation
Science, Volume 392, Issue 6798, May 2026.
Human DHX29 detects nonoptimal codon usage to regulate mRNA stability
Science, Volume 392, Issue 6798, May 2026.
Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration
Science, Volume 392, Issue 6798, May 2026.