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RETRACTION: The 12-15-Lipoxygenase is a Modulator of Alzheimer's-Related Tau Pathology In Vivo

1 week 6 days ago
P. F. Giannopoulos, Y. B. Joshi, J. Chu, and D. Praticò, "The 12-15-Lipoxygenase is a Modulator of Alzheimer's-Related Tau Pathology In Vivo," Aging Cell 12, no. 6 (2013): 1082-1090, https://doi.org/10.1111/acel.12136. The above article, published online on 17 July 2013 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Monty Montano; The Anatomical Society; and John Wiley & Sons Ltd. The retraction has been agreed upon...

Unequal healthy ageing trajectories across Europe: socioeconomic development and age-related disease burden in the European Union and South-Eastern European countries

1 week 6 days ago
Although life expectancy has increased, many of the added years are lived in poor health, highlighting growing inequalities in ageing trajectories. Despite the increasing need for ageing-related health strategies, non-EU European countries remain underrepresented in comparative research, leaving limited evidence on healthy ageing disparities between EU and South-Eastern European (SEE) nations. This study explored variations in key health and socioeconomic indicators of societal ageing and...
Nora Kovacs

A telomere-lipid-immunity axis linking viral integration to autoimmune disease risk

1 week 6 days ago
Autoimmune diseases rise steeply with biological aging, reflecting progressive failure of immune regulation. Inherited chromosomally integrated human herpesvirus 6 (iciHHV-6) represents a unique lifelong viral exposure in which the viral genome is embedded within host telomeres, potentially altering leukocyte telomere length (LTL), a core biomarker of immune aging. Circulating metabolites may further modify these viral-telomeric interactions. We analyzed 156,927 UK Biobank participants free of...
May A Beydoun