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This common vitamin deficiency can mimic normal aging

2 weeks 1 day ago
Vitamin B12 is needed in microscopic amounts, but a shortage can have major effects on health and energy. The vitamin was first linked to a lifesaving liver treatment for pernicious anemia nearly 100 years ago. Today, researchers are finding that B12 may also help keep cellular powerhouses called mitochondria functioning properly. This could explain why some people experience fatigue and brain fog even before traditional signs of deficiency show up.

Disrupted brain functional network topology and potential network reorganization in early-stage Parkinson's disease with probable REM sleep behavior disorder

2 weeks 1 day ago
CONCLUSION: Early PD + pRBD exhibit specific and more severe neurofunctional network impairment pattern. Characterized by more significantly disrupted neurofunctional network topology and widespread functional connectivity abnormalities across multiple brain networks, with potential functional network reorganization. These functioning abnormalities may serve as imaging biomarkers for this clinically malignant subtype and provide potential neurobiological mechanism for understanding its poorer...
Congli Huang

From plastics to pathology: The neurodegenerative impact of Bisphenol-A on Alzheimer's disease

2 weeks 1 day ago
Bisphenol-A (BPA), a ubiquitous component of polycarbonate plastics and epoxy resins, has emerged as a significant environmental risk factor for neurodegenerative diseases, particularly Alzheimer's disease (AD). It is widely detected in the environment and humans due to its extensive use in plastics and epoxy resins for consumer products such as bottles, containers, and tableware. This review synthesizes current evidence on the molecular and cellular mechanisms by which BPA exposure may...
Sneha Kumari