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CONCLUSIONS: The findings suggest that digital interventions tailored to the sociocultural needs of older adults may play an important role in promoting healthy aging and supporting mental well-being in India. Stakeholder-informed digital modules addressing physical health, sleep, emotional well-being, social connectedness, and self-care practices may enhance engagement, accessibility, and preventive mental healthcare among older adults. Future research should evaluate the effectiveness,...

First public presentation of studies on environmental factors touts rigorous science amid charged political climate

More than 1,000 genetic switches behave differently in male and female immune cells, helping explain why women are much more vulnerable to autoimmune diseases such as lupus. Female immune systems appear genetically tuned for stronger inflammatory responses—a powerful defense against infection that may also make dangerous immune misfires more likely.

Researchers have developed a new way to turn ordinary antibodies into tiny disease-fighting molecules that can work inside human cells, potentially opening new paths for treating Alzheimer’s, Parkinson’s, Huntington’s disease, and motor neurone disease.

ChatGPT and other AIs use a flood of facts, and the occasional lie, to persuade humans

The brain has a remarkably flexible system for handling uncertainty and changing situations. Researchers found that the frontoparietal cortex constantly shifts how it communicates with other brain regions depending on what information is needed to make a decision. Rather than simply becoming more active when things get difficult, this network appears to reorganize itself in real time.

Scientists have found evidence that the effects of a mother’s age on her offspring may be driven by reversible changes in gene activity rather than permanent DNA damage. The discovery raises the fascinating possibility that biological information from mothers, grandmothers, and even great-grandmothers can shape the health of future generations.