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Realization of 2D metals at the ångström thickness limit
A robustly rooted tree of eukaryotes reveals their excavate ancestry
An operating system for executing applications on quantum network nodes
TGFβ links EBV to multisystem inflammatory syndrome in children
Perception of viral infections and initiation of antiviral defence in rice
Genomic determinants of antigen expression hierarchy in African trypanosomes
High temporal variability not trend dominates Mediterranean precipitation
Weather anomalies cannot explain insect decline
Sapphire anvils squeeze metals atomically-thin
How fast your brain ages is affected by these 64 genes
Watch DeepMind’s AI robot slam-dunk a basketball
Robotic fingers can tell objects apart by touch
Reply to: Weather anomalies cannot explain insect decline
Author Correction: Observation of Nagaoka polarons in a Fermi–Hubbard quantum simulator
Climate finding endangered, USDA freezes Maine, and vax stat deciphered: Trump Tracker
Follow President Donald Trump’s impact on U.S. research and science globally
Beyond-classical computation in quantum simulation
Science, Volume 388, Issue 6743, Page 199-204, April 2025.
Congress comes down to the wire to keep U.S. government open
Republicans seek yearlong spending bill with provisions Democrats oppose
Response of neuronal populations to phase-locked stimulation: model-based predictions and validation
Modulation of neuronal oscillations holds promise for the treatment of neurological disorders. Nonetheless, conventional stimulation in a continuous open-loop manner can lead to side effects and suboptimal efficiency. Closed-loop strategies such as phase-locked stimulation aim to address these shortcomings by offering a more targeted modulation. While theories have been developed to understand the neural response to stimulation, their predictions have not been thoroughly tested using...
The deubiquitinase USP45 inhibits autophagy through actin regulation by Coronin 1B
The autophagy-lysosomal system comprises a highly dynamic and interconnected vesicular network that plays a central role in maintaining proteostasis and cellular homeostasis. In this study, we uncovered the deubiquitinating enzyme (DUB), dUsp45/USP45, as a key player in regulating autophagy and lysosomal activity in Drosophila and mammalian cells. Loss of dUsp45/USP45 results in autophagy activation and increased levels of V-ATPase to lysosomes, thus enhancing lysosomal acidification and...
The sex-specific difference in age-related aortic regional morphological changes
CONCLUSION: A sex-based variation in the rate of aortic morphological aging is observed throughout the lifespan, with females showing more pronounced changes in aortic tortuosity. It highlights the importance of prioritizing preventive measures for females, who may benefit more due to sex-specific disparities.