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Reference values for gait speed, five-times-sit-to-stand test, balance, and handgrip strength: analysis of data from the English Longitudinal Study of Ageing
Simple performance-based tests such as gait speed, the Five-Times-Sit-to-Stand Test (FTSST), balance tests, and handgrip strength are associated with health outcomes. We aimed to establish age- and sex-specific reference (normative) values for these tests in the English population. Adults aged ≥ 50 years (female n = 4,234; male n = 3,424) from the English Longitudinal Study of Ageing were included. Weighted percentiles ranging from the 5th to the 95th percentile [P5-95] were calculated. Best...
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Science, Volume 391, Issue 6788, February 2026.
Erratum for the Report “Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations”
Science, Volume 391, Issue 6788, February 2026.
Cryo–electron microscopic visualization of RAD51 filament assembly and end-capping by XRCC3-RAD51C-RAD51D-XRCC2
Science, Volume 391, Issue 6788, February 2026.
Organism-wide cellular dynamics and epigenomic remodeling in mammalian aging
Science, Volume 391, Issue 6788, February 2026.
Reconstitution of sex determination and the testicular niche using mouse pluripotent stem cells
Science, Volume 391, Issue 6788, February 2026.
Different DNA repair pathways support intact or truncated insertions by R2 retrotransposon protein
Science, Volume 391, Issue 6788, February 2026.
A cellular basis for the mammalian nocturnal-diurnal switch
Science, Volume 391, Issue 6788, February 2026.
Convergent and lineage-specific genomic changes shape adaptations in sugar-consuming birds
Science, Volume 391, Issue 6788, February 2026.
STING–NF-κB signaling builds an influenza spillover barrier
Science, Volume 391, Issue 6788, February 2026.