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MRI-based multi-organ clocks for healthy aging and disease assessment
Biological aging clocks across organ systems and tissues have advanced understanding of human aging and disease. In this study, we expand this framework to develop seven magnetic resonance imaging-based multi-organ biological age gaps (MRIBAGs), including the brain, heart, liver, adipose tissue, spleen, kidney and pancreas. Using data from 313,645 individuals curated by the MULTI Consortium, we link the seven MRIBAGs to 2,923 plasma proteins, 327 metabolites and 6,477,810 common genetic...
A brief digital cognitive test improves Alzheimer's disease detection
No abstract
Daily briefing: How the brain locks in long-term memories
This gene causes obesity — and shields against heart disease
Global health is in crisis — who will step in to fix it?
The problem with career planning in science
Parenting, illnesses and medical commitments: the private details grant reviewers shouldn’t need to know
A single blood test could reveal the biological stage of Alzheimer’s disease
Trojan gold: New US “standard” is another veiled attack on science
Science, Volume 390, Issue 6770, October 2025.
Head-direction cells as a neural compass in bats navigating outdoors on a remote oceanic island
Science, Volume 390, Issue 6770, October 2025.
High-resolution spatial mapping of cell state and lineage dynamics in vivo with PEtracer
Science, Volume 390, Issue 6770, October 2025.
Global mean sea level over the past 4.5 million years
Science, Volume 390, Issue 6770, October 2025.
“Kiss-shrink-run” unifies mechanisms for synaptic vesicle exocytosis and hyperfast recycling
Science, Volume 390, Issue 6770, October 2025.
Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning
Science, Volume 390, Issue 6770, October 2025.
Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics
Science, Volume 390, Issue 6770, October 2025.
A mosaic of modular variation at a single gene underpins convergent plumage coloration
Science, Volume 390, Issue 6770, October 2025.
In Science Journals
Science, Volume 390, Issue 6770, Page 251-253, October 2025.
Mobilizing capital and technology for a clean aviation industry
Science, Volume 390, Issue 6770, Page 242-245, October 2025.
A view of Horizon Europe’s future
Science, Volume 390, Issue 6770, Page 217-217, October 2025.
Chaos and confusion as U.S. shutdown drags on
Science, Volume 390, Issue 6770, Page 228-229, October 2025.