Aggregator

Mechanisms to medicines: navigating drug repurposing strategies in Alzheimer's disease

2 months 3 weeks ago
Alzheimer's disease (AD) represents a continuously advancing neurodegenerative condition distinguished by the unremitting deterioration of cognitive abilities and memory impairment, which significantly hampers daily functioning of life. In the absence of disease modifying treatments, it continues to pose a significant global challenge. Though symptomatic treatment exists, the inherent complexity involved with AD pathogenesis related to Aβ plaques, neurofibrillary tangles, neuroinflammation,...
Sara Akhtar Khan

Gapless pangenome analyses reveal fast Brassica rapa subspeciation

2 months 3 weeks ago
Science, Volume 391, Issue 6785, February 2026.
Wei Ma, Yuanming Liu, Xiaochun Wei, Xiaomeng Zhang, Xiaonan Li, Zhaokun Liu, Lingyun Yuan, Guangguang Li, Shu Zhang, Qihang Yang, Xiaocong Chang, Zizhuo Han, Hao Liang, Zhaoshui Luan, Qianyun Wang, Yujie Gu, Xinlong Wang, Xianlei Zhao, Qing Liu, Xiaoxue…

Why methane surged in the atmosphere during the early 2020s

2 months 3 weeks ago
Science, Volume 391, Issue 6785, February 2026.
P. Ciais, Y. Zhu, Y. Cai, X. Lan, S. E. Michel, B. Zheng, Y. Zhao, D. A. Hauglustaine, X. Lin, Y. Zhang, S. Sun, X. Tian, M. Zhao, Y. Wang, J. Chang, X. Dou, Z. Liu, R. Andrew, C. A. Quinn, B. Poulter, Z. Ouyang, W. Yuan, K. Yuan, Q. Zhu, F. Li, N. Pan,…

DNA origami vaccines program antigen-focused germinal centers

2 months 3 weeks ago
Science, Volume 391, Issue 6785, February 2026.
Anna Romanov, Grant A. Knappe, Larance Ronsard, Christopher A. Cottrell, Yiming J. Zhang, Heikyung Suh, Lauren Duhamel, Marjan Omer, Asheley P. Chapman, Katie Spivakovsky, Patrick Skog, Claudia T. Flynn, Jeong Hyun Lee, Oleksandr Kalyuzhniy, Alessia…