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In Other Journals

2 months 2 weeks ago
Science, Volume 390, Issue 6775, Page 800-800, November 2025.
Corinne Simonti, and Jesse Smith, Sacha Vignieri, Sarah Lemprière, Joana Osório, Jesse Smith, Michael A. Funk, Di Jiang, and Sumin Jin

Time to laugh

2 months 2 weeks ago
Science, Volume 390, Issue 6775, Page 858-858, November 2025.
Lindsey Smith Taillie

Atomic layer bonding contacts in two-dimensional semiconductors

2 months 2 weeks ago
Science, Volume 390, Issue 6775, Page 813-818, November 2025.
Li Gao, Zhangyi Chen, Zhenghui Fang, Shucao Lu, Xiaofu Wei, He Jiang, Kuanglei Chen, Xiaoyu He, Chao Chen, Wei Shangguan, Jinsen Shang, Huihui Yu, Mengyu Hong, Yang He, Xiankun Zhang, Zheng Zhang, Yue Zhang

An ode to change

2 months 2 weeks ago
Science, Volume 390, Issue 6775, Page 792-792, November 2025.
Viviane Callier

Vision and Cognitive Difficulties From Midlife to Late Life: Findings From the National Health Interview Survey

2 months 2 weeks ago
ObjectivesTo examine whether the association between vision and cognitive difficulties varies by age group.MethodsWe analyzed pooled data from the 2021-2023 National Health Interview Survey, including 52,582 U.S. adults aged 45 and older. Vision and cognitive difficulties were based on self-reports. Logistic regression with interaction terms assessed age-related differences.ResultsVision difficulty was reported by 22.7% of respondents. It was associated with over twice the odds of cognitive...
Daniel Jung

Utilizing accelerated and delayed murine models of aging to address the "healthspan issue" - A review of skeletal muscle health

2 months 2 weeks ago
The gap between lifespan and healthspan is increasing globally, resulting in millions of individuals spending additional years burdened by frailty or disease. This disparity, paired with the increasingly aged populations of Western nations, poses a palpable predicament to public health and the economy. Deterioration of the skeletal muscle system is a key contributor to illness, loss of independence, and diminishing healthspan. Muscle quality correlates to longevity due to its significant role in...
Matthew J Johnston

PRDX1 promotes testosterone synthesis and attenuates aging via redox regulation of ATG4B to modulate lipophagy

2 months 2 weeks ago
Testosterone insufficiency disrupts spermatogenesis and expedites male aging. Autophagy facilitates testosterone synthesis. However, a molecular reduction mechanism of autophagy-related protein 4 homolog B (ATG4B) has not been established. Herein, we reveal that peroxiredoxin 1 (PRDX1) is clinically associated with male fertility disorders. Adult mutant mice with Leydig cell (LC)-specific deletion of the Prdx1 gene exhibit premature testicular aging and infertility. A series of in vivo and in...
Hanbin Zhang