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NAD(+) precursor supplementation in human ageing: clinical evidence and challenges

2 months 2 weeks ago
Nicotinamide adenine dinucleotide (NAD^(+)) is an essential molecule involved in cellular metabolism, and its decline has been implicated in ageing and age-related disorders. However, evidence for an age-related decline in NAD^(+) levels in humans has been consistently observed only in a limited number of studies. Similarly, although preclinical studies support the idea that supplementation with NAD^(+) precursors is a promising therapeutic strategy to promote healthy ageing, human clinical...
Kasper T Vinten