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Scientists restore memory by blocking a single Alzheimer’s protein
Researchers have identified a new potential weapon against Alzheimer’s: blocking a protein called PTP1B. In mice, this approach boosted memory and helped brain immune cells clear harmful plaque buildup. Since PTP1B is also linked to diabetes and obesity—both risk factors for Alzheimer’s—it could offer a broader treatment strategy.
Scientists reveal the best exercise for knee arthritis pain relief
A major review of 217 trials shows that aerobic exercise is the most effective option for managing knee osteoarthritis. Activities like walking, cycling, and swimming outperformed other exercise types in reducing pain and improving movement. While alternatives like strength training and mind-body exercises help, they are best used alongside aerobic workouts. The findings also confirm that exercise is a safe and essential part of treatment.
Measles explodes in Bangladesh after vaccination breakdown, killing hundreds of children
Changes to government’s vaccine purchase system after 2024 revolution led to nationwide shortages, gaps in immunity
Daily briefing: ‘A true pioneer and maverick’, Craig Venter dead at 79
US lawmakers vote to reject Trump’s massive budget cuts — but call for substantial decreases
Why cows burp methane: new ‘cellular organ’ discovered in gut microbes
‘Beyond COP’ climate summit puts scientists at the centre of the action
All life runs on 20 amino acids. These cells run key machinery on just 19
Forest pests hit trees hard as temperatures rise
Blood test hints at breast-tumour response to treatment
Continuously graded-doped SnO<sub>2</sub> for efficient n–i–p perovskite solar cells
To defeat gerrymandering, we must go back to the drawing board
Science, Volume 392, Issue 6797, April 2026.
Deeper detection limits in astronomical imaging using self-supervised spatiotemporal denoising
Science, Volume 392, Issue 6797, April 2026.
Bypassing the yellow phase for extremely stable formamidinium lead iodide perovskite solar cells
Science, Volume 392, Issue 6797, April 2026.
Toward life with a 19–amino acid alphabet through generative artificial intelligence design
Science, Volume 392, Issue 6797, April 2026.
Gene syntax defines supercoiling-mediated transcriptional feedback
Science, Volume 392, Issue 6797, April 2026.
Rumen ciliates modulate methane emissions in ruminants
Science, Volume 392, Issue 6797, April 2026.
Disordered protein LAT encodes relative levels of signaling pathways in T cell activation
Science, Volume 392, Issue 6797, April 2026.
Lymphoid tissue chemokines limit priming duration to preserve CD8+ T cell functionality
Science, Volume 392, Issue 6797, April 2026.