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The worst El Niño in recorded history is brewing — here’s how governments must prepare
All the ways a cell can die — and why the variety matters
Hundreds of ‘free’ academic journals have started charging fees
Watch scientists decipher burned scrolls without unrolling them
A global safety net for climate-risk intelligence is urgently needed
Why insects need their own protected areas
Biosecurity must protect human functional capacity
Submerged land bridge may have helped people cross the Mediterranean
A campaign to map and sample the bridge could help reconstruct ancient animal migrations
Single wildfire smoke exposure causes lasting harm, monkey study suggests
Infant macaques showed immune changes and signs of faster aging years after inhaling smoke
One of nature’s greatest marine wonders may be about to vanish
An algal bloom has almost wiped out a unique population of giant cuttlefish—and their stunning mating swarms
Brain scans reveal a possible cause of long COVID fatigue and brain fog
Researchers have found evidence that long COVID may damage dopamine releasing neurons in the brain, potentially explaining persistent fatigue, low motivation, slowed movement, and memory difficulties. The discovery could lead to new treatments that target the brain's dopamine system.
DNA analysis strengthens evidence that Thomas Jefferson fathered children with Sally Hemings
Researchers sequenced president’s genome from a lock of hair taken shortly after his death, then compared his DNA with that of Hemings’s living descendants
Giant telescope project rejects La Palma as backup site
U.S.-led Thirty Meter Telescope declines €1 billion Spanish offer to build the observatory on the Canary Islands
Stem cells reverse stroke damage and restore movement in mice
Stem cell transplants helped regenerate stroke-damaged brain tissue in mice, producing new neurons and restoring lost motor function. The treatment also improved blood vessels, inflammation, and the blood-brain barrier, raising hopes that a similar approach could eventually help repair the human brain after stroke.
Stopping Ozempic may raise heart attack and stroke risk
A large study suggests the cardiovascular benefits of GLP-1 drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound can disappear surprisingly quickly when treatment stops. After two years off the medications, patients had a 22% higher risk of heart attack, stroke, and death compared with those who stayed on them.
Scientists create a needle-thin brain implant that can do three jobs at once
A new needle-thin brain implant can record neural activity, deliver drugs, and stimulate multiple brain regions using a single flexible fiber. Successful tests in mice suggest it could give scientists a more precise, less invasive way to study the brain and may eventually help treat neurological disorders such as epilepsy.
Chronic stress may be quietly reshaping your heart
Chronic inflammation tied to stress, lifestyle, mental health, and socioeconomic conditions may silently change the heart for years before any symptoms appear. People with the highest inflammation levels faced a 43% greater risk of heart attack and stroke, raising hopes that earlier testing and anti-inflammatory treatments could help prevent serious heart disease.
This dolphin chased a fish until it puked—then ate the vomit
The behavior, known as kleptoparasitism, marks one of the few well-documented examples of a cetacean stealing food
Stanford scientists discover the human brain may actually be two separate organs
Scientists have found that the human brain develops from two distinct cellular systems, suggesting that evolution fused together two ancient nervous systems with very different jobs. The discovery also allowed researchers to grow human hindbrain neurons in the lab, opening new possibilities for studying ALS, spinal muscular atrophy, and other brainstem diseases.
A somatic checkpoint through NHR-49/HNF4alpha governs reproductive investment and longevity in C. elegans
The nuclear hormone receptor NHR-49, a homolog of mammalian PPARα and HNF4α, is a key transcriptional regulator of nutrition sensing and fatty acid metabolism in Caenorhabditis elegans. Here, we examine the role of NHR-49 in reproduction, including oocyte activation and ovulation. Loss of NHR-49 causes inappropriate oocyte activation and laying of unfertilized oocytes in the absence of sperm, resulting in rapid loss of yolk and stored fat, and drastic shortening of lifespan. Conversely,...