Aggregator
The GNPC provides a proteomic resource for biomarker discovery and mechanistic insight in neurodegenerative disease
One potent gene raises risk of Alzheimer’s, Parkinson’s and other brain diseases
Low-quality papers based on public health data are flooding the scientific literature
The mysterious missing ingredient in the highest-energy cosmic rays
Monster black hole merger is biggest ever seen
Why the global economy is more uncertain than ever, and what to do about it
Bring science into business schools to train the leaders of tomorrow
Without science, there can be no development
Critical commentaries such as ‘Matters arising’ have flawed formats
China’s journal ranking system stands up to scrutiny
Invest in data resources to make FAIR a reality
Map endemic species before they vanish unrecorded
A canine friend to a feline family
Disease burden, lifetime healthcare cost and long-term intervention impact projections among older adults in Singapore
Smart brain-zapping implants could revolutionize Parkinson’s treatment
Large study of scientists who move their labs reveals how location drives productivity
Concentrating funding at high-powered universities can maximize output, paper argues, but may sacrifice broader benefits
Molecular fossils offer first glimpse of how life survived Snowball Earth
Overlooked rock samples from 640 million years ago record microbes hanging on beneath frozen oceans
Paleontologist to lead U.S. national academy
The prestigious organization faces funding challenges and political controversies
‘Something remarkable has happened’: Cancer treatments bolster evidence of a natural HIV cure
In exclusive chat with Science, Loreen Willenberg describes remaining HIV-free even after immune-suppressing therapies for brain and lung tumors
The Rab3 family proteins in age-related neurodegeneration: unraveling molecular pathways and potential therapeutic targets
The Rab3 protein family is composed of a series of small GTP-binding proteins, including Rab3a, Rab3b, Rab3c, and Rab3d, termed Rab3s. They play crucial roles in health, including in brain function, such as through the regulation of synaptic transmission and neuronal activities. In the high-energy-demanding and high-traffic neurons, the Rab3s regulate essential cellular processes, including trafficking of synaptic vesicles and lysosomal positioning, which are pivotal for the maintenance of...