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Optical nonlinearities in excess of 500 through sublattice reconstruction
Complete computational design of high-efficiency Kemp elimination enzymes
Unsupervised pretraining in biological neural networks
Flight simulator for moths reveals they navigate by starlight
These moths use the stars to navigate on an epic migration
Reply to: On the effects of fault alignment on slip stability
On the effects of fault alignment on slip stability
Editorial Expression of Concern: Transformation of primary human endothelial cells by Kaposi’s sarcoma-associated herpesvirus
Strategies for climate-resilient global wind and solar power systems
Is a monster web of ocean currents headed for collapse? The race is on to find out
Author Correction: Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome
For the first time, women scientists win $1 million climate research prize
Following criticism for all-male winners in the past, women earned two of the three Frontiers Planet Prizes this year
This giant, all-seeing telescope is set to revolutionize astronomy
The Vera C. Rubin Observatory will build an unprecedented map of the universe—and discover billions of fast-changing objects
The proteome of the late Middle Pleistocene Harbin individual
Science, Volume 389, Issue 6761, Page 704-707, August 2025.
Updated: Trump administration unfreezes, then refreezes, NIH funding to Columbia University
Morning agency email indicating resumption of hundreds of millions in grants is quickly undone
Will long-lasting HIV preventive be a game changer—or a missed opportunity?
FDA’s approval of lenacapavir comes at a time when global health cuts could stall its rollout
U.S. researchers are speaking up for science in local newspapers
Through two grassroots efforts, more than 80 op eds have been published in news outlets across the country
‘Truly amazing’: Octopuses ‘taste’ harmful microbes with their suckers
Unique ability allows the animals to protect themselves and their offspring from decaying food and other material
FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression
Approximately 35% of US adults over 65 are obese, highlighting the need for therapies targeting age-related metabolic issues. Fibroblast growth factor 21 (FGF21), a hormone mainly produced by the liver, improves metabolism and extends lifespan. To explore its effects without developmental confounders, we generated mice with adipocyte-specific FGF21 overexpression beginning in adulthood. When fed a high-fat diet, these mice lived up to 3.3 years, resisted weight gain, improved insulin...
Ovarian aging at single-cell resolution: Current paradigms and perspectives
Ovarian failure is a key event in female reproductive aging, resulting in the depletion of follicular reserve and a decline in fertility. In addition, it triggers systemic pathological changes, including osteoporosis and cardiovascular disease, due to decreased estrogen levels. Despite extensive study, mapping senescent ovarian cells is challenging due to the multicellular composition and heterogeneity of the ovary. In the past decade, single-cell resolution technologies have provided new...