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In Other Journals

8 months 2 weeks ago
Science, Volume 387, Issue 6736, Page 838-839, February 2025.

Corinne Simonti, and
Jesse Smith,
Di Jiang,
Melissa McCartney,
Bianca Lopez,
Sarah Lemprière,
Ian S. Osborne,
Sarah H. Ross, and
Jack Huang

Comic relief

8 months 2 weeks ago
Science, Volume 387, Issue 6736, Page 902-902, February 2025.

Avraneel Paul

Unscrambling the cellular and molecular threads of Neuroplasticity: Insights into Alzheimer's disease pathogenesis

8 months 2 weeks ago
Alzheimer's disease (AD) is predominantly the most recurring and devastating neurological condition among the elderly population, characterized by the accumulation of amyloid-β (Aβ) and phosphorylated tau proteins, and is accompanied by progressive decline of learning and memory. Due to its complex and multifactorial etiology, a wide variety of therapeutic interventions have been developed. Despite constant advancements in the field, effective treatments that ameliorate the severity of...
Palak Kalra

Drug repurposing for Alzheimer's disease and other neurodegenerative disorders

8 months 2 weeks ago
Repurposed drugs provide a rich source of potential therapies for Alzheimer's disease (AD) and other neurodegenerative disorders (NDD). Repurposed drugs have information from non-clinical studies, phase 1 dosing, and safety and tolerability data collected with the original indication. Computational approaches, "omic" studies, drug databases, and electronic medical records help identify candidate therapies. Generic repurposed agents lack intellectual property protection and are rarely advanced to...
Jeffrey L Cummings

Unscrambling the cellular and molecular threads of Neuroplasticity: Insights into Alzheimer's disease pathogenesis

8 months 2 weeks ago
Alzheimer's disease (AD) is predominantly the most recurring and devastating neurological condition among the elderly population, characterized by the accumulation of amyloid-β (Aβ) and phosphorylated tau proteins, and is accompanied by progressive decline of learning and memory. Due to its complex and multifactorial etiology, a wide variety of therapeutic interventions have been developed. Despite constant advancements in the field, effective treatments that ameliorate the severity of...
Palak Kalra