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Poleward greening of the global oceans
Science, Volume 388, Issue 6753, Page 1274-1275, June 2025.
In Other Journals
Science, Volume 388, Issue 6753, Page 1288-1288, June 2025.
Torn between two worlds
Science, Volume 388, Issue 6753, Page 1342-1342, June 2025.
Cholinergic feedback for modality- and context-specific modulation of sensory representations
Science, Volume 388, Issue 6753, Page 1324-1329, June 2025.
Molecular evolution of sour tolerance in birds
Science, Volume 388, Issue 6753, Page 1330-1336, June 2025.
Limitations of chemical monitoring hinder aquatic risk evaluations on the macroscale
Science, Volume 388, Issue 6753, Page 1301-1305, June 2025.
Excision of organic macrocycles from covalent organic frameworks
Science, Volume 388, Issue 6753, Page 1318-1323, June 2025.
Efficient super-reducing organic photoredox catalysis with proton-coupled electron transfer mitigated back electron transfer
Science, Volume 388, Issue 6753, Page 1294-1300, June 2025.
In vivo CAR T cell generation to treat cancer and autoimmune disease
Science, Volume 388, Issue 6753, Page 1311-1317, June 2025.
Greener green and bluer blue: Ocean poleward greening over the past two decades
Science, Volume 388, Issue 6753, Page 1337-1340, June 2025.
New books from outer space, future Earth, and close to home
Science, Volume 388, Issue 6753, Page 1264-1270, June 2025.
New approach enables body to engineer its own cells to fight cancer or autoimmunity
Injections of mRNA may offer a simpler, cheaper way to build powerful CAR-T cells
No sour faces: How birds evolved to eat highly acidic fruits
Genetic mutations more than 20 million years ago helped birds tolerate the tart and broaden their diets
‘Dragon Man’ skull belongs to mysterious human relative
At long last, scientists have a nearly complete cranium from hominins known as Denisovans
U.S. National Academies adopts new business model to weather a financial storm
Realignment of major program units aims to improve efficiency and make up for loss of federal contracts
This moth makes its epic migration navigating by starlight
Bogong moths fly 1000 kilometers orienting to stars and the Milky Way, an ability never seen before in invertebrates
Transferability of European-derived Alzheimer's disease polygenic risk scores across multiancestry populations
A polygenic score (PGS) for Alzheimer's disease (AD) was derived recently from data on genome-wide significant loci in European ancestry populations. We applied this PGS to populations in 17 European countries and observed a consistent association with the AD risk, age at onset and cerebrospinal fluid levels of AD biomarkers, independently of apolipoprotein E locus (APOE). This PGS was also associated with the AD risk in many other populations of diverse ancestries. A cross-ancestry polygenic...
alpha-Synuclein pathology in LRRK2 Parkinson disease
No abstract
Rapamycin, Not Metformin, Mirrors Dietary Restriction-Driven Lifespan Extension in Vertebrates: A Meta-Analysis
Dietary restriction (DR) robustly increases lifespan across taxa. However, in humans, long-term DR is difficult to maintain, leading to the search for compounds that regulate metabolism and increase lifespan without reducing caloric intake. The magnitude of lifespan extension from two such compounds, rapamycin and metformin, remains inconclusive, particularly in vertebrates. Here, we conducted a meta-analysis comparing lifespan extension conferred by rapamycin and metformin to DR-mediated...
Reversible proliferative arrest induced by rapid depletion of RNase MRP
Cellular quiescence is a state of reversible proliferative arrest that plays essential roles in development, resistance to stress, aging, and longevity of organisms. Here we report that rapid depletion of RNase MRP, a deeply conserved RNA-based enzyme required for rRNA biosynthesis, induces a long-term yet reversible proliferative arrest in human cells. Severely compromised biogenesis of rRNAs along with acute transcriptional reprogramming precede a gradual decline of the critical cellular...