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Pattern recognition in the nucleation kinetics of non-equilibrium self-assembly
Autoreactive T cells target peripheral nerves in Guillain–Barré syndrome
Tuning commensurability in twisted van der Waals bilayers
Alternative splicing of latrophilin-3 controls synapse formation
Multifunctional ytterbium oxide buffer for perovskite solar cells
Affinity-optimizing enhancer variants disrupt development
This AI just figured out geometry — is this a step towards artificial reasoning?
Sulphur dioxide in the mid-infrared transmission spectrum of WASP-39b
A small and vigorous black hole in the early Universe
Age-related noncanonical TRMT6–TRMT61A signaling impairs hematopoietic stem cells
The consciousness wars: can scientists ever agree on how the mind works?
Could giant underwater curtains slow ice-sheet melting?
Uprooted Ukrainian scientists may never return from their new research homes
As war drags on, officials ponder how to coax academics back to regions the country hopes to recapture
New undersea robot digitally captures the sea’s most delicate life
Combining advanced imaging, sequencing, and collecting technologies paves the way for better species descriptions
Dogged by climate change and human hunters, a mammoth’s life is written in her tusks
Elma’s travels offer rare glimpse into the challenges that drove her species to extinction
A promising snakebite treatment seemed ready for prime time. Then, it backfired
Researchers publish first-ever report of antibody-dependent enhancement of snake venom toxin as a warning to others developing new treatments
Risk of COVID-19 death in adults who received booster COVID-19 vaccinations in England
The emergence of the COVID-19 vaccination has been critical in changing the course of the COVID-19 pandemic. To ensure protection remains high in vulnerable groups booster vaccinations in the UK have been targeted based on age and clinical vulnerabilities. We undertook a national retrospective cohort study using data from the 2021 Census linked to electronic health records. We fitted cause-specific Cox models to examine the association between health conditions and the risk of COVID-19 death and...
NAD<sup>+</sup> dependent UPR<sup>mt</sup> activation underlies intestinal aging caused by mitochondrial DNA mutations
Aging in mammals is accompanied by an imbalance of intestinal homeostasis and accumulation of mitochondrial DNA (mtDNA) mutations. However, little is known about how accumulated mtDNA mutations modulate intestinal homeostasis. We observe the accumulation of mtDNA mutations in the small intestine of aged male mice, suggesting an association with physiological intestinal aging. Using polymerase gamma (POLG) mutator mice and wild-type mice, we generate male mice with progressive mtDNA mutation...
How solute atoms control aqueous corrosion of Al-alloys
Aluminum alloys play an important role in circular metallurgy due to their good recyclability and 95% energy gain when made from scrap. Their low density and high strength translate linearly to lower greenhouse gas emissions in transportation, and their excellent corrosion resistance enhances product longevity. The durability of Al alloys stems from the dense barrier oxide film strongly bonded to the surface, preventing further degradation. However, despite decades of research, the individual...
Meta-analysis shows no consistent evidence for senescence in ejaculate traits across animals
Male reproductive traits such as ejaculate size and quality, are expected to decline with advancing age due to senescence. It is however unclear whether this expectation is upheld across taxa. We perform a meta-analysis on 379 studies, to quantify the effects of advancing male age on ejaculate traits across 157 species of non-human animals. Contrary to predictions, we find no consistent pattern of age-dependent changes in ejaculate traits. This result partly reflects methodological limitations,...