Aggregator
In Other Journals
Science, Volume 389, Issue 6765, Page 1105-1105, September 2025.
My lucky detour
Science, Volume 389, Issue 6765, Page 1158-1158, September 2025.
Fragmentation increased in over half of global forests from 2000 to 2020
Science, Volume 389, Issue 6765, Page 1151-1156, September 2025.
Fire heat affects the impacts of wildfires on air pollution in the United States
Science, Volume 389, Issue 6765, Page 1137-1142, September 2025.
Structural basis for LZTR1 recognition of RAS GTPases for degradation
Science, Volume 389, Issue 6765, Page 1112-1117, September 2025.
Microcanonical kinetics of water-mediated proton transfer in microhydrated 4-aminobenzoic acid
Science, Volume 389, Issue 6765, Page 1143-1146, September 2025.
A main-group metal carbonyl complex: Structure and isomerization to a carbene-stabilized tin atom
Science, Volume 389, Issue 6765, Page 1118-1121, September 2025.
Drop-printing with dynamic stress release for conformal wrap of bioelectronic interfaces
Science, Volume 389, Issue 6765, Page 1127-1132, September 2025.
Genomic signatures indicate biodiversity loss in an endemic island ant fauna
Science, Volume 389, Issue 6765, Page 1133-1136, September 2025.
Rapid establishment of species barriers in plants compared with that in animals
Science, Volume 389, Issue 6765, Page 1147-1150, September 2025.
Behind the scenes of scientific fraud
Science, Volume 389, Issue 6765, Page 1096-1096, September 2025.
Restoring trust in science
Science, Volume 389, Issue 6765, Page 1095-1095, September 2025.
Great Britain’s economy didn’t completely tank after Romans left, countering conventional wisdom
“Completely surprising” discovery based on ancient pollutants suggests mining and smelting continued apace for centuries
NIH kicks off yearlong effort to modernize biosafety policies
New initiative leaves researchers with questions about details and scope
Weird rings of DNA fuel cancers. This scientist leads the effort to target them
Paul Mischel and others are testing therapies for rogue genetic loops that drive tumor evolution and growth
Scientists directly date dino eggshells for the first time
The new findings narrow age estimates for the clutch of eggs—and may help identify which species laid them
Strongest black hole collision yet confirms theories of Einstein, Hawking
Observation confirms that a black hole’s area can only grow and never shrink
The role of the gut microbiota in neuropsychiatric disorders and therapy
The vast microbial community residing in the gut is known as the gut microbiota (GM). Alterations in the compositional equilibrium of the GM, a phenomenon termed GM dysbiosis, have been increasingly associated with the pathogenesis of various diseases, particularly neuropsychiatric disorders. The microbiota-gut-brain axis (MGBA) serves as a bidirectional communication system that connects the gut to the brain. Notably, several prevalent neuropsychiatric disorders, including depression,...
ABCA7 variants impact phosphatidylcholine and mitochondria in neurons
Loss-of-function variants in the lipid transporter ABCA7 substantially increase the risk of Alzheimer's disease^(1,2), yet how they impact cellular states to drive disease remains unclear. Here, using single-nucleus RNA-sequencing analysis of human brain samples, we identified widespread gene expression changes across multiple neural cell types associated with rare ABCA7 loss-of-function variants. Excitatory neurons, which expressed the highest levels of ABCA7, showed disrupted lipid metabolism,...
Senescent-like border-associated macrophages regulate cognitive aging via migrasome-mediated induction of paracrine senescence in microglia
Aging is a major risk factor for various neurological disorders, including Alzheimer's disease, and is associated with the accumulation of senescent cells, which can themselves propagate the senescence process through paracrine signaling. Migrasomes are organelles that form during cellular migration, detach from parent cells and mediate intercellular communication. Here we demonstrate that border-associated macrophages (BAMs) acquire senescence-associated properties during early brain aging,...