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James Fraser Stoddart obituary: chemist and nanotechnology pioneer who built molecular machines
Breaking up clusters of circulating tumour cells to halt cancer spread
Did giant ice age beasts carve these vast caves in South America?
Withdrawing funds from US vaccination programmes will worsen crisis of trust in public-health science
No parent–child conflicts about when young cichlid fish leave home
India’s ‘One Nation’ publishing agreement is transformational — but beware inequities
Industrial projects in Chile threaten clear views of the Universe
Canada’s postgraduate funding gap is still yawning even after budget increases
Nectar-robbing bees commit floral larceny
Author Correction: Gut microbiota strain richness is species specific and affects engraftment
Author Correction: Lithocholic acid phenocopies anti-ageing effects of calorie restriction
Author Correction: An RNA-dependent RNA polymerase formed by TERT and the <i>RMRP</i> RNA
Author Correction: Continental influx and pervasive matrilocality in Iron Age Britain
Ancient human genomes offer clues about the earliest migrations out of Africa
Our remote fieldwork taught us how to band together as scientists
Trump executive order puts STEM diversity efforts on hold
Scientists engaged in work to make research fields more inclusive face canceled contracts and expired grants
Is your research on Trump’s spending hit list?
How the White House’s pause in federal spending could affect academic science
Trump executive order would upend federal surveys that ask about gender identity
“You’re completely erasing nonbinary, gender-diverse people,” one researcher says
New Zealand shakes up its research system in bid to boost economic growth
Major reorganization draws mixed reviews from researchers
Splicing accuracy varies across human introns, tissues, age and disease
Alternative splicing impacts most multi-exonic human genes. Inaccuracies during this process may have an important role in ageing and disease. Here, we investigate splicing accuracy using RNA-sequencing data from >14k control samples and 40 human body sites, focusing on split reads partially mapping to known transcripts in annotation. We show that splicing inaccuracies occur at different rates across introns and tissues and are affected by the abundance of core components of the spliceosome...