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Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice
While previous research has demonstrated the therapeutic efficacy of telomerase reverse transcriptase (TERT) overexpression using adeno-associated virus and cytomegalovirus vectors to combat aging, the broader implications of TERT germline gene editing on the mammalian genome, proteomic composition, phenotypes, lifespan extension, and damage repair remain largely unexplored. In this study, we elucidate the functional properties of transgenic mice carrying the Tert transgene, guided by precise...
China’s ‘dreamy’ new ship aims for Earth’s mantle—and assumes ocean-drilling leadership
As U.S.-led program falters, Meng Xiang prepares for bold mission to drill 7 kilometers below the sea floor
With venerable ship’s retirement, U.S.-led ocean-drilling program ends
JOIDES Resolution stripped of equipment after budget gap left unfilled