Skip to main content

Aggregator

Klotho deficiency and cognitive impairment in dialysis patients: mechanisms, clinical evidence, and therapeutic implications

3 weeks 2 days ago
Cognitive impairment is highly prevalent among patients with end-stage renal disease (ESRD), particularly those undergoing dialysis, and is associated with poor clinical outcomes and reduced quality of life. Emerging evidence suggests that Klotho, an anti-aging protein predominantly expressed in the kidney, plays a critical role in the pathophysiology of uremia-related cognitive dysfunction. This review summarizes current clinical and experimental evidence regarding Klotho deficiency in dialysis...
Weiwei Hu

Creatine doesn't just build muscle. It may also help fight cancer

3 weeks 2 days ago
Scientists have discovered that creatine may strengthen one of the immune system's most important cancer-fighting pathways by energizing dendritic cells that activate killer T cells. The promising results could eventually help make immunotherapy more effective, but they have not yet been tested in human patients.