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Life history is a key driver of temporal fluctuations in tropical tree abundances

5 months 1 week ago
The question of what mechanisms maintain tropical biodiversity is a critical frontier in ecology, intensified by the heightened risk of biodiversity loss faced in tropical regions. Ecological theory has shed light on multiple mechanisms that could lead to the high levels of biodiversity in tropical forests. But variation in species abundances over time may be just as important as overall biodiversity, with a more immediate connection to the risk of extirpation and biodiversity loss. Despite the...
Kenneth Jops

A tough soft-hard interface in the human knee joint driven by multiscale toughening mechanisms

5 months 1 week ago
Joining heterogeneous materials in engineered structures remains a significant challenge due to stress concentration at interfaces, which often leads to unexpected failures. Investigating the complex, multiscale-graded structures found in animal tissue provides valuable insights that can help address this challenge. The human meniscus root-bone interface is an exemplary model, renowned for its exceptional fatigue resistance, toughness, and interfacial adhesion properties throughout its lifespan....
Wenyue Li

Propagation of pathologic alpha-synuclein from kidney to brain may contribute to Parkinson's disease

5 months 1 week ago
The pathogenesis of Lewy body diseases (LBDs), including Parkinson's disease (PD), involves α-synuclein (α-Syn) aggregation that originates in peripheral organs and spreads to the brain. PD incidence is increased in individuals with chronic renal failure, but the underlying mechanisms remain unknown. Here we observed α-Syn deposits in the kidneys of patients with LBDs and in the kidney and central nervous system of individuals with end-stage renal disease without documented LBDs. In male mice,...
Xin Yuan