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Graphene-polymer reinforcement of perovskite lattices for durable solar cells
Science, Volume 387, Issue 6738, Page 1069-1077, March 2025.
Ultrafast on-demand exciton formation in a single-molecule junction by tailored terahertz pulses
Science, Volume 387, Issue 6738, Page 1077-1082, March 2025.
Macroevolutionary divergence of gene expression driven by selection on protein abundance
Science, Volume 387, Issue 6738, Page 1063-1068, March 2025.
Mandrel-free fabrication of giant spring-index and stroke muscles for diverse applications
Science, Volume 387, Issue 6738, Page 1101-1108, March 2025.
Catalytic remodeling of complex alkenes to oxonitriles through C=C double bond deconstruction
Science, Volume 387, Issue 6738, Page 1083-1090, March 2025.
Oxidative amination by nitrogen atom insertion into carbon-carbon double bonds
Science, Volume 387, Issue 6738, Page 1108-1114, March 2025.
Rapid butterfly declines across the United States during the 21st century
Science, Volume 387, Issue 6738, Page 1090-1094, March 2025.
Upslope plant species shifts in Mesoamerican cloud forests driven by climate and land use change
Science, Volume 387, Issue 6738, Page 1058-1063, March 2025.
Plants from the planetary past
Science, Volume 387, Issue 6738, Page 1045-1045, March 2025.
Artificial intelligence speaks up
Science, Volume 387, Issue 6738, Page 1046-1046, March 2025.
Oceans’ deepest trenches are home to ‘incredible’ diversity
In trio of studies, scientists explore life in the mysterious hadal zone
New NIH grant terminations target transgender studies—even in mice
Science has identified more than two dozen halted grants amid Trump’s transgender crackdown, right as NIH suspends its own researchers who worked on topic
Butterfly populations are plummeting across the United States
Even common species have become much less abundant in just 20 years, a large analysis reveals
How often are children genetically unrelated to their presumed fathers?
Tackling a touchy subject, genetic detective finds only 1% of European children have unexpected paternity
News at a glance: Science societies stand up, an asteroid threat fades, and a commercial lunar lander touches down
The latest in science and policy
Supreme Court upholds lower court’s order to ‘unfreeze’ $2 billion in foreign aid
Decision is a victory for organizations that provide humanitarian assistance, but its impact is unclear
Human ancestors invented a bone toolkit much earlier than previously thought
At least some early hominins leapt from stone to bone technology some 1.5 million years ago
Phosphorylated tau 181 and 217 are elevated in serum and muscle of patients with amyotrophic lateral sclerosis
Blood phosphorylated (p)-tau 181 and p-tau 217 have been proposed as accurate biomarkers of Alzheimer's disease (AD) pathology. However, blood p-tau 181 is also elevated in amyotrophic lateral sclerosis (ALS) without a clearly identified source. We measured serum p-tau 181 and p-tau 217 in a multicentre cohort of ALS (n = 152), AD (n = 111) cases and disease controls (n = 99) recruited from four different centres. Further, we investigated the existence of both p-tau species using...
Tau filaments with the Alzheimer fold in human MAPT mutants V337M and R406W
Frontotemporal dementia (FTD) and Alzheimer's disease (AD) are the most common forms of early-onset dementia. Unlike AD, FTD begins with behavioral changes before the development of cognitive impairment. Dominantly inherited mutations in MAPT, the microtubule-associated protein tau gene, give rise to cases of FTD and parkinsonism linked to chromosome 17. These individuals develop abundant filamentous tau inclusions in brain cells in the absence of β-amyloid deposits. Here, we used cryo-electron...
Age-related differences in long-term memory performance and astrocyte morphology in rat hippocampus
Astrocytes are neuromodulator cells. Their complex and dynamic morphology regulates neuronal signaling, synaptic plasticity, and neurogenesis. The impact of aging on astrocyte morphology is still under ongoing debate. Therefore, this study aimed to characterize astrocyte morphology in the hippocampus of older rats. 2-, 18-, and 20-month-old male Wistar rats were submitted to the object recognition test to assess their short- and long-term memories. CA1, CA2, CA3, and the dentate gyrus were...