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Dysfunction in primate dorsolateral prefrontal area 46 affects motivation and anxiety
Science, Volume 389, Issue 6762, Page 840-844, August 2025.
Overcoming energy disorder for cavity-enabled energy transfer in vibrational polaritons
Science, Volume 389, Issue 6762, Page 845-848, August 2025.
Ultrafast elastocapillary fans control agile maneuvering in ripple bugs and robots
Science, Volume 389, Issue 6762, Page 811-817, August 2025.
Ultracompact on-chip spectral shaping using pixelated nano-opto-electro-mechanical gratings
Science, Volume 389, Issue 6762, Page 806-810, August 2025.
Increasing global human exposure to wildland fires despite declining burned area
Science, Volume 389, Issue 6762, Page 826-829, August 2025.
The quantum metric of electrons with spin-momentum locking
Science, Volume 389, Issue 6762, Page 822-825, August 2025.
Electrical coherent driving of chiral antiferromagnet
Science, Volume 389, Issue 6762, Page 830-834, August 2025.
Fitness benefits of genetic rescue despite chromosomal differences in an endangered pocket mouse
Science, Volume 389, Issue 6762, Page 835-839, August 2025.
Discovering Denisova
Science, Volume 389, Issue 6762, Page 788-788, August 2025.
Mutualism—here, there, and everywhere
Science, Volume 389, Issue 6762, Page 787-787, August 2025.
By-product recovery from US metal mines could reduce import reliance for critical minerals
Science, Volume 389, Issue 6767, Page 1325-1331, September 2025.
Vegetation steers a river’s path
Science, Volume 389, Issue 6763, Page 879-880, August 2025.
Vegetation changes the trajectory of river bends
Science, Volume 389, Issue 6763, Page 915-920, August 2025.
DNA from ancient bones reveals how Indigenous Americans got their mucus
Neanderthals and Denisovans passed along gene that provides a sticky shield against germs
Driven by the pain of endometriosis, this scientist is uncovering clues to its causes
Katie Burns is helping reveal the immune system’s role in the long-neglected disease
Watch this oil droplet bounce endlessly, like a tiny basketball
Dancing droplets could lead to new ways to control fluids and might even provide insight into quantum mechanics
Neutrino astronomers set biggest traps ever for messengers from cosmic accelerators
Country-size array of radio antennas could trace ultra–high-energy particles back to supernovae and black holes
Control of immune response in an iPSC-based allogeneic cell therapy clinical trial for Parkinson's disease
Because the central nervous system (CNS) is an immune-privileged organ, it requires different immunosuppression strategies for cell therapies using induced pluripotent stem cells (iPSCs) compared with ones for organ transplantations. We recently conducted the first in-human clinical trial of a cell therapy for Parkinson's disease using allogeneic iPSCs (jRCT number: jRCT2090220384). All patients were transplanted with dopaminergic neural progenitors differentiated from iPSCs (iPSC-DANs), which...
The role of mitophagy in perioperative neurocognitive disorder: from mechanisms to implications
Perioperative neurocognitive disorder (PND) is a significant neurological complication in aging perioperativepatients, seriously impacting their postoperative recovery and cognition as well as quality of life. The occurrence of PND is closely related to various factors, including neuroinflammation and oxidative stress, while the exact mechanism is still unknown. Mitophagy is a specialized form of autophagy and maintains cellular homeostasis by selectively degrading damaged and dysfunctional...
Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics
Light can serve as a tunable trigger for neurobioengineering technologies, enabling probing, control, and enhancement of brain function with unmatched spatiotemporal precision. Yet, these technologies often require genetic or structural alterations of neurons, disrupting their natural activity. Here, we introduce the Graphene-Mediated Optical Stimulation (GraMOS) platform, which leverages graphene's optoelectronic properties and its ability to efficiently convert light into electricity. Using...