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Negative social ties as emerging risk factors for accelerated aging, inflammation, and multimorbidity
Negative social ties, or "hasslers," are pervasive yet understudied components of social networks that may accelerate biological aging and morbidity. Using ego-centric network data and DNA methylation-based biological aging clocks (i.e., DunedinPACE and age-accelerated GrimAge2) from saliva from a state representative probability sample in Indiana, we examine how negative social ties are associated with accelerated biological aging and a broad range of health outcomes, including inflammation and...
From survival to longevity: Healthy dietary patterns and risk of premature aging in survivors of childhood cancer
No abstract
This glass wafer could back up your phone—and last 10,000 years
Laser-written patterns on glass could store data for millennia at a time
Associations between declines in uneven terrain walking speed and visuospatial working memory in older adults
CONCLUSION: These findings support a relationship between declines in uneven terrain mobility and n-back cognitive function in older adults; however, this relationship was not observed in younger adults. Further research is needed to understand the shared neural mechanisms underlying age-related declines in mobility and cognitive function.
Circadian rhythms in aging and longevity: from molecular chronomics to translational gerontology
Aging is accompanied by progressive deterioration in physiological homeostasis, increasing vulnerability to metabolic, neurodegenerative, cardiovascular, and immune disorders. Over the past two decades, circadian biology has emerged as a central integrative framework linking environmental time cues to cellular, tissue, and organismal resilience. The circadian timing system (CTS), composed of a central pacemaker in the suprachiasmatic nucleus (SCN) and peripheral clocks throughout the body,...