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The Role of the Glymphatic System in Alzheimer's Disease: Mechanisms, Evidence, and Therapeutic Implications
Alzheimer's disease (AD) is an aging-associated neurodegenerative disorder characterized by amyloid-β (Aβ) and tau accumulation and progressive cognitive decline. Increasing evidence implicates the glymphatic system, a brain-wide perivascular pathway involved in cerebrospinal fluid-interstitial fluid exchange and metabolic waste clearance, in the removal of Aβ, tau, and other solutes relevant to AD pathogenesis. Aging-related alterations in aquaporin-4 polarization, arterial pulsatility, sleep...
Analysis of Quantitative Susceptibility Mapping Data for Multi-Site and Multi-Modal Brain Imaging Studies: For Measuring Brain Iron and Its Changes with Age
CONCLUSION: The selection of QSM reconstruction pipelines impacts results obtained from multi-site studies, indicating the importance of harmonizing QSM pipelines when interpreting susceptibility measures across studies.
‘Invisible’ birds spotted with thermal imaging
Approach could help reveal which migrating species are most vulnerable to wind turbines and light pollution