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Resting-state brain activity and association with physical activity
CONCLUSION: Different physical activity intensities were not significantly associated with resting-state functional connectivity of various brain networks in a sample of healthy older adults. This finding contrasts with the results of previous cross-sectional studies.
Lipid dysregulation as a convergent pathway linking environmental exposures to stroke
Stroke remains the second leading cause of death globally, yet traditional risk factors explain only 50-60 percent of cases. Emerging evidence indicates that lipid dysregulation is a central mechanism linking environmental exposures to cerebrovascular vulnerability. Aging, chronic inflammation, infections, diet, inactivity, stress, sleep disorders, and toxins are associated with disruption of lipid homeostasis through oxidative stress-induced lipid peroxidation, cytokine-mediated metabolic...