Aggregator
Why this neuroscientist is taking the plunge into science advocacy
The World Bank is right to prioritize reproducibility
How countries can grow without impoverishing future generations
‘Mother of Hubble’: how Nancy Grace Roman ushered in a new era of astronomy
A data leak shut a top research biobank: lessons from the recovery
The Kelvin scale’s creator William Thomson made many scientific advances
Limit bets on clinical-trial outcomes being placed on prediction markets
Sideline vested interests to reform China’s research
Nepal disaster is a wake-up call to take compound climate risks seriously
Put patients at the centre of medical AI governance
Author Correction: Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
Two children died from gene therapies in China: where the field goes next
China’s fast-track clinical trials are in the spotlight after child deaths
Stereoselective polysubstituted bicyclo[1.1.0]butane synthesis by rhodium-catalyzed kinetic resolution
Science, Ahead of Print.
With billion-dollar project, China maps scars of its geological past
Early results from SinoProbe II hint at how continental fragments assemble and evolve
U.S. cancer institute director counters gloomy forecast
Anthony Letai denies political interference during his first year and says NCI's grant numbers are up again
Why are human births so difficult? Male babies—not just upright walking—may be to blame
Analysis of 140 species suggests the risks of sons are offset by evolutionary advantages
Scientists discover a hidden immune signal that helps spinal cords regrow
A surprising immune system signal may help explain why zebrafish can regenerate damaged spinal cords so effectively. Researchers found that certain neutrophils release Il-4, which calms harmful inflammation and allows injured nerve fibers to grow again. Without these cells, healing stalled, but adding Il-4 restored regeneration. Scientists now want to know whether the same mechanism could someday be harnessed to improve spinal cord repair in humans.
Common dry-cleaning chemical linked to triple the risk of liver scarring
A chemical commonly used in dry cleaning and found in some household products may be an overlooked threat to liver health. Researchers found that people with detectable levels of tetrachloroethylene (PCE) in their blood were three times more likely to have significant liver fibrosis, a dangerous buildup of scar tissue that can eventually lead to liver failure or cancer. The risk climbed sharply as PCE levels increased, even after accounting for factors such as age, sex, race, education, alcohol use, and metabolic conditions.
Adaptive oncogenesis of β-catenin emerges from declining liver tissue integrity
Mutations are fundamental to oncogenesis, yet they cannot fully explain cancer progression, as oncogenic mutations frequently accumulate in healthy tissues without immediate malignancy. In the liver, β-catenin mutations are highly prevalent in hepatocellular carcinoma but are widely considered weak or cooperative drivers, raising the question of how their oncogenic potential is contextually regulated. Aging and chronic injury are major determinants of cancer risk. However, how declining tissue...