Aggregator
A unified framework for systematic curation and evaluation of aging biomarkers
Cell populations in human breast cancers are molecularly and biologically distinct with age
Aging represses oncogenic KRAS-driven lung tumorigenesis and alters tumor suppression
Hospital-treated infectious diseases and the risk of epilepsy in older age
A synthetic oocyte aging method for uncovering the molecular origins of egg aneuploidy
<cite>Science</cite>’s ‘Dance Your Ph.D.’ contest is open again—with an all new, AI twist
For the first time, there’s a special prize for a research-themed dance generated by an artificial intelligence program
How the rush for critical minerals is neglecting human needs
Climate change is devastating mining of minerals needed to fight it
Japan’s first female prime minister doesn’t call herself a feminist — but the country needs her to tackle sexism in science
China should undertake more risky research to close the Nobel gap
Can AI predict and limit online hate?
When will Africa have a Nobel prize in medicine?
Safeguards for virology must be designed in partnership with the public
Have physicists finally solved the ‘golfer’s curse’?
Team says it has hit on an explanation for heartbreaking “lip outs”
U.K. science sector is ‘bleeding to death,’ lawmakers say in report
House of Lords committee urges government to stem exodus of science and technology companies
Main U.S. funder of physical sciences chops down advisory panels, alarms researchers
Scientists fear merger of Department of Energy advisory committees that gave them their voices at agency
Forests are migrating up mountain peaks
Satellite imagery reveals an unexpected shift in tree lines—but it may not have anything to do with climate change
Towards pharmacological prevention of Alzheimer disease
Prevention of Alzheimer disease (AD) is a medical challenge owing to its complex pathogenesis, which involves amyloid-β (Aβ) and tau aggregation, neuroinflammation and progressive neurodegeneration. Development of disease-specific biomarkers has transformed our ability to detect AD pathology early, enabling more accurate diagnosis, monitoring and the development of targeted disease-modifying therapies. Consequently, primary and secondary prevention of AD have become feasible goals. In this...
Alzheimer's decline slows with just a few thousand steps a day
No abstract
Physical activity as a modifiable risk factor in preclinical Alzheimer's disease
Physical inactivity is a recognized modifiable risk factor for Alzheimer's disease (AD), yet its relationship with progression of AD pathology in humans remains unclear, limiting the effective translation into prevention trials. Using pedometer-measured step counts in cognitively unimpaired older adults, we demonstrated an association between higher physical activity and slower cognitive and functional decline in individuals with elevated baseline amyloid. Importantly, this beneficial...