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‘Targeted and belittled’: scientists at US environmental agency speak out as layoffs begin
NASA embraced diversity. Trump’s DEI purge is hitting space scientists hard
Bats on film: scientific storytelling from a recovering academic
Why I retracted part of my PhD dissertation
‘Researching climate change feels like standing in the path of an approaching train’
Neuroevolution insights into biological neural computation
Science, Volume 387, Issue 6735, February 2025.
Conformational ensembles reveal the origins of serine protease catalysis
Science, Volume 387, Issue 6735, February 2025.
KLF2 maintains lineage fidelity and suppresses CD8 T cell exhaustion during acute LCMV infection
Science, Volume 387, Issue 6735, February 2025.
Enhancer-driven cell type comparison reveals similarities between the mammalian and bird pallium
Science, Volume 387, Issue 6735, February 2025.
Developmental origins and evolution of pallial cell types and structures in birds
Science, Volume 387, Issue 6735, February 2025.
Evolutionary convergence of sensory circuits in the pallium of amniotes
Science, Volume 387, Issue 6735, February 2025.
‘Wrecking ball’: RFK Jr. moves to fire thousands of health agency employees
Supervisors deliver bad news across NIH, CDC
U.S. conditionally approves vaccine to protect poultry from avian flu
The decision brings U.S. poultry farmers a step closer to immunizing their flocks
Abandoned crops, fired scientists: Agricultural research hit by U.S. foreign aid freeze
A court ruling may temporarily ease funding problems, but for many projects the long term outlook remains uncertain
Senate confirms Robert F. Kennedy Jr., a vaccine opponent, as health secretary
Controversial attorney will oversee vast health research and drug safety programs
Renowned scientific integrity investigator endows fund to support fellow sleuths
Microbiologist Elisabeth Bik donates $200,000 to support training, travel
Binary and weighted network analysis and its applications to functional connectivity in subjective memory complaints: A resting-state fMRI approach
CONCLUSION: The findings suggest that functional impairments in SMC patients might be associated with disruptions in the global and regional topological organization of the brain's functional connectome, offering new and significant insights into the pathophysiological mechanisms underlying SMC.
Association of Cancer Status, Functional Outcomes, and Mortality in Australian Geriatric Rehabilitation Patients, RESORT
CONCLUSIONS AND IMPLICATIONS: Although inpatient mortality is higher in active cancer patients, older adults with active cancer who survive until inpatient geriatric rehabilitation discharge achieve similar functional gains and rates of discharge to the community. Functional improvement is of prognostic value in active cancer patients.
Interactive Associations of Age, Apolipoprotein E ε4 Gene, Physical Activity, and Physical Functioning on Processing Speed
CONCLUSIONS AND IMPLICATIONS: Our findings underscore the complex interplay among physical activity, physical functioning, age, and genetic risk on processing speed. The protective associations of higher PAEE levels and better physical functioning, especially in older APOE4 carriers, suggest that maintaining an active lifestyle and mobility may be crucial for individuals with a genetic predisposition to cognitive decline.
News from the old: Aging features in the intracardiac, musculoskeletal, and enteric nervous systems
Aging strongly affects the peripheral nervous system (PNS), triggering alterations that vary depending on the innervated tissue. The most frequent alteration in peripheral nerve aging is reduced nerve fiber and glial density which can lead to abnormal nerve functionality. Interestingly, the activation of a destructive phenotype takes place in macrophages across the PNS while a reduced number of neuronal bodies is a unique feature of some enteric ganglia. Single cell/nucleus RNA-sequencing has...