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300,000-year-old wooden tools from Gantangqing, southwest China
Science, Volume 389, Issue 6755, Page 78-83, July 2025.
Identification of proliferating neural progenitors in the adult human hippocampus
Science, Volume 389, Issue 6755, Page 58-63, July 2025.
Random unitaries in extremely low depth
Science, Volume 389, Issue 6755, Page 92-96, July 2025.
Consistent energy-diversity relationships in terrestrial vertebrates
Science, Volume 389, Issue 6755, Page 53-57, July 2025.
Fluorine-free strongly dipolar polymers exhibit tunable ferroelectricity
Science, Volume 389, Issue 6755, Page 69-72, July 2025.
Coupled, decoupled, and abrupt responses of vegetation to climate across timescales
Science, Volume 389, Issue 6755, Page 64-68, July 2025.
Electric double-layer synthesis of a spongelike, lightweight reticular membrane
Science, Volume 389, Issue 6755, Page 73-77, July 2025.
The intracellular Ca2+ sensitivity of transmitter release in glutamatergic neocortical boutons
Science, Volume 389, Issue 6755, Page 48-52, July 2025.
Membrane topology inversion of GGCX mediates cytoplasmic carboxylation for antiviral defense
Science, Volume 389, Issue 6755, Page 84-91, July 2025.
The brain in motion
Science, Volume 389, Issue 6755, Page 35-35, July 2025.
Rejecting genetic essentialism
Science, Volume 389, Issue 6755, Page 36-36, July 2025.
Strong interactions and isospin symmetry breaking in a supermoiré lattice
Science, Volume 389, Issue 6761, Page 736-740, August 2025.
Journal plagued with problematic papers, likely from paper mills, pauses submissions
The halt will let Taylor &Francis focus on checking Bioengineered’s papers for fraudulent works and paid authorships
NIH restores grants to South Africa scientists, adds funding option for other halted foreign projects
A policy tweak to the ban on foreign “subawards” should allow clinical trials worldwide to continue
Genetic evidence that our brains make new neurons in adulthood may close a century-old debate
Cells from human brain tissue have genetic hallmarks of neural progenitors, AI-aided study finds
Ancient wooden tools show human ancestors ate their veggies
Found in China, 300,000-year-old digging sticks reveal a lost technology
Researchers claim their AI model simulates the human mind. Others are skeptical
Cognitive scientists question new Centaur model’s ability to predict human behavior
Increased Risk of Dementia and its Subtypes following Various Forms of Acquired Brain Injury: a Meta-analysis and Systematic Review
In recent years, acquired brain injuries (ABIs) have been implicated in the development and pathogenesis of dementia; however, existing data is conflicting and often lacks precise classifications or comprehensive analyses. This review sought to synthesize available evidence to assess the association between four major ABI types-traumatic brain injury (TBI), cerebral atherosclerosis (AS), intracranial hemorrhage, and ischemic stroke-and risk of subsequent all-cause dementia (ACD) and dementia...
Rethinking TREM2 as a target for Alzheimer's disease after the INVOKE-2 trial failure
No abstract
Cardiolipin-mimic lipid nanoparticles without antibody modification delivered senolytic in vivo CAR-T therapy for inflamm-aging
mRNA-based in vivo chimeric antigen receptor (CAR)-T cell engineering offers advantages over ex vivo therapies, including streamlined manufacturing and transient expression. However, current delivery methods require antibody-modified vehicles with manufacturing challenges. In this study, inspired by cardiolipin, we identify cardiolipin-like di-phosphoramide lipids that improve T cell transfection without targeting ligands, both in vitro and in vivo. The T cell-favored tropism is likely due to...