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Connection, not perfection
Science, Volume 386, Issue 6724, Page 934-934, November 2024.
Mechanically strong yet metabolizable supramolecular plastics by desalting upon phase separation
Science, Volume 386, Issue 6724, Page 875-881, November 2024.
Ship collision risk threatens whales across the world’s oceans
Science, Volume 386, Issue 6724, Page 870-875, November 2024.
NREM sleep improves behavioral performance by desynchronizing cortical circuits
Science, Volume 386, Issue 6724, Page 892-897, November 2024.
Amidination of ligands for chemical and field-effect passivation stabilizes perovskite solar cells
Science, Volume 386, Issue 6724, Page 898-902, November 2024.
Hidden state inference requires abstract contextual representations in the ventral hippocampus
Science, Volume 386, Issue 6724, Page 926-932, November 2024.
Nature of metal-support interaction for metal catalysts on oxide supports
Science, Volume 386, Issue 6724, Page 915-920, November 2024.
Direct hearing measurements in a baleen whale suggest ultrasonic sensitivity
Science, Volume 386, Issue 6724, Page 902-906, November 2024.
Whole-brain spatial transcriptional analysis at cellular resolution
Science, Volume 386, Issue 6724, Page 907-915, November 2024.
Chloronitramide anion is a decomposition product of inorganic chloramines
Science, Volume 386, Issue 6724, Page 882-887, November 2024.
Population connectivity shapes the distribution and complexity of chimpanzee cumulative culture
Science, Volume 386, Issue 6724, Page 920-925, November 2024.
Nature’s gift economies
Science, Volume 386, Issue 6724, Page 858-858, November 2024.
Portraits of the Universe
Science, Volume 386, Issue 6724, Page 857-857, November 2024.
Physicists borrow from origami to extend range of dark matter search
Expandable “metamaterial” makes axion detector more sensitive in higher mass range
Unearthed university investigation found research ethics failings at French medical institute
Studies conducted by Didier Raoult and colleagues flouted French and international ethical standards, report concludes
News at a glance: Russian brain drain, Trump’s nominees, and a long-distance traveler goes extinct
The latest in science and policy
Do ‘blue zones,’ supposed havens of longevity, rest on shaky science?
Critics say extraordinary life spans reflect faulty record keeping, not healthy lifestyles
Light-powered catalysts destroy ‘forever chemicals’
Reactions point toward cheaper remediation of fluorine compounds that contaminate the environment
Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
Progranulin (PGRN) deficiency is linked to neurodegenerative diseases, including frontotemporal dementia (FTD), Alzheimer's disease, and Parkinson's disease. Proper PGRN levels are critical for brain health; however, the function of PGRN is unclear. PGRN is composed of 7.5 repeat domains, called granulins, and processed into granulins inside the lysosome. PGRN is beneficial for neuronal health, but the role of individual granulins is controversial and unclear. We find that the expression of...
Muscarinic receptors mediate motivation via preparatory neural activity in humans
Motivation depends on dopamine, but might be modulated by acetylcholine which influences dopamine release in the striatum, and amplifies motivation in animal studies. A corresponding effect in humans would be important clinically, since anticholinergic drugs are frequently used in Parkinson's disease, a condition that can also disrupt motivation. Reward and dopamine make us more ready to respond, as indexed by reaction times (RT), and move faster, sometimes termed vigour. These effects may be...