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How to stop a looming ‘splinternet’
Seven work–life balance tips from a part-time PhD student
Author Correction: Immune system adaptation during gender-affirming testosterone treatment
The global H5N1 influenza panzootic in mammals
Yo-yo dieting accelerates cardiovascular disease by reprogramming the immune system
We must train specialists in botany and zoology — or risk more devastating extinctions
What is a cell type, really? The quest to categorize life’s myriad forms
We can’t recreate ancient wilderness environments — but that’s not the point
Mathematics helped Britain to get in touch with continental Europe a century ago
Gender inequity persists among journal chief editors
Floating homes need social and political acceptance in the Western world
More measures needed to ease funding competition in China
The human heart shows signs of ageing after just a month in space
Gaza: Why is it so hard to establish the death toll?
U.S. health agency seeks to bar grant funding to prominent biologist David Sabatini
Finding of former Whitehead Institute biologist’s sexual misconduct “antithetical” to NIH’s standards for grantees, department says
Some octopuses treat fish like hunting buddies
The usually solitary creatures collaborate with—and sometimes wallop—fish while scouring for prey
A mile-high probiotic? Gut microbe may help lowlanders conquer high altitudes
Common in people living at great elevations, a type of bacterium reduces damage caused by low oxygen levels
Screening the active ingredients of plants via molecular docking technology and evaluating their ability to reduce skin photoaging
The active ingredients of plants were screened by molecular docking technology and the result were verified. According to the verification results of molecular docking, the five active ingredients were combined in equal proportions to form a compound drug. In the HaCaT photoaging model, the effects of the compound drug on antioxidant and senescence-associated secretory phenotype (SASP) factors of the NF-κB and MAPK pathways were studied via SOD and MDA kits, DCFH-DA fluorescent probes and ELISA....
Contributions and future potential of animal models for geroscience research on sensory systems
Sensory systems mediate our social interactions, food intake, livelihoods, and other essential daily functions. Age-related decline and disease in sensory systems pose a significant challenge to healthy aging. Research on sensory decline in humans is informative but can often be difficult, subject to sampling bias, and influenced by environmental variation. Study of animal models, including mice, rats, rabbits, pigs, cats, dogs, and non-human primates, plays a complementary role in biomedical...
Age-induced changes in skeletal muscle mitochondrial DNA synthesis, quantity, and quality in genetically unique rats
Mitochondrial genomic integrity is a key element of physiological processes and health. Changes in the half-life of the mitochondrial genome are implicated in the generation and accumulation of age-induced mitochondrial DNA (mtDNA) mutations, which are implicated in skeletal muscle aging and sarcopenia. There are conflicting data on the half-life of mtDNA, and there is limited information on how aging affects half-life in skeletal muscle. We hypothesized that skeletal muscle mtDNA synthesis...