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Daily briefing: The brain deploys immune cells at the mere sight of sickness
Columbia researchers eager to restart science after university’s deal with Trump
Could machine learning help to build a unified theory of cognition?
Scientists mourn Tom Lehrer — nerdiest of singer-songwriters
Cell’s sugar coating mapped at below-nanometre resolution
Could bridging science and the arts be the key to better policies?
How to detect consciousness in people, animals and maybe even AI
AI models are neglecting African languages — scientists want to change that
Africa needs to invest in science communication — here’s how
Can science address painters’ problems?
The Virtual Lab of AI agents designs new SARS-CoV-2 nanobodies
Serum amyloid P secreted by bone marrow adipocytes drives skeletal amyloidosis
How China’s bold talent recruitment has shaped science
Early universe’s ‘little red dots’ may be black hole stars
Puzzling objects spotted by NASA’s JWST telescope may be entirely new class of celestial entity
Giant virus with record-long tail discovered in Pacific Ocean
Infecting marine plankton, the pathogen may use its extreme appendage to enter host cells
Prevalence and risk factors of abuse among older adults registered with health centers in Southern Tehran: a population-based study
CONCLUSION: The high prevalence underscores the need for routine screening in health centers and caregiver education programs.
Why space foods aren't just for space
No abstract
The 18S rRNA methyltransferase DIMT-1 regulates lifespan in the germline later in life
Specialized ribosomes help determine which proteins are synthesized, however, the influence of age on ribosome heterogeneity and whether dysregulation of this process drives organismal aging is unknown. Here we examined the role of ribosomal RNA (rRNA) methylation in maintaining appropriate translation as organisms age. In a directed RNAi screen, we identified 18S rRNA N6'-dimethyl adenosine (m^(6,2)A) methyltransferase, dimt-1, as a regulator of C. elegans lifespan and stress resistance. We...
Reevaluating the role of education on cognitive decline and brain aging in longitudinal cohorts across 33 Western countries
Why education is linked to higher cognitive function in aging is fiercely debated. Leading theories propose that education reduces brain decline in aging and enhances tolerance to brain pathology or that it does not affect cognitive decline but, rather, reflects higher early-life cognitive function. To test these theories, we analyzed 407,356 episodic memory scores from 170,795 participants older than 50 years, alongside 15,157 brain magnetic resonance imaging scans from 6,472 participants...
Peak oxygen uptake in older adults with heart failure: a systematic review and meta-analysis
Reduced peak oxygen uptake (V̇O₂peak) is a hallmark of heart failure (HF) and aging, but studies on V̇O₂peak in older HF patients are limited. We compared V̇O₂peak in older HF patients versus controls and investigated differences across the age continuum: young-old (YO, 60-69 years), middle-old (MO, 70-79 years), and oldest-old (OO, ≥ 80 years). PubMed was searched (1967 May 2024) for studies meeting the following inclusion criteria: (1) HF patients with mean age ≥ 65 years; (2) V̇O₂peak...