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Unveiling mysteries of aging: the potential of melatonin in preventing neurodegenerative diseases in older adults
Neurodegenerative conditions, including Alzheimer's disease, Parkinson's disease, and Huntington's disease, result in a substantial health problem for the elderly, marked by ongoing neuronal degeneration and a deterioration in mental faculties. These disorders are frequently linked to oxidative stress, problems with mitochondria, and persistent inflammation in the brain, which worsen neuronal damage. The neurohormone melatonin, primarily secreted by the pineal gland, has gained recognition as a...
Calorie restriction mimetics against aging and inflammation
Geroprotectors, a class of compounds that ameliorate molecular, cellular, or physiological aging-related alterations, have garnered significant attention in the quest to promote healthy aging and extend the human health span. Among these, Calorie Restriction Mimetics (CRMs) have emerged as promising candidates due to their potential to mimic the benefits of calorie restriction, a dietary approach involving reduced calorie intake without malnutrition. Prospective CRMs may include biguanides...
How fast were dinosaurs? These mud-covered birds may show us
Researchers used live birds to test a 50-year-old way of estimating dino speeds from fossil footprints
These squirrels’ scaly tails help them climb slippery trees
The grippy appendages may help engineers design robots that can navigate dense forests
Daily briefing: How to make America healthy — the real problems and how to fix them
Boys surpass girls in maths in the first year of school
In the face of anti-science politics, silence is not without cost
Structural and functional characterization of human sweet taste receptor
Publisher Correction: Transposable element methylation tracks age
How to make America healthy: the real problems — and best fixes
We need to predict the people disasters will hit, not just the places
Celebrating the anniversary of Michael Faraday’s discovery of benzene
Adversarial collaborations: all theories must be subject to critical evaluation
Make the study of human flourishing a global priority
‘Harm’ must not be redefined by US conservation agencies
House Democrats slam RFK Jr. for research funding cuts, vaccine policy
Health secretary claims to be unaware of letter of protest from 300 of his agency’s scientists
A single shot of a flu drug could outperform vaccines—and protect for an entire season
One injection of a long-lasting drug showed up to 76% efficacy in a large trial
Mountain-dwelling animals may have a worse sense of smell
Poor olfaction could be an adaptation to frigid environments
Roman gravestones hint that ancient economies still shape the present
A computer analysis of Latin inscriptions argues that economic complexity is “sticky” over time. Historians are skeptical
Sound policy demands sound science
Science, Volume 389, Issue 6755, Page 7-7, July 2025.