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Two long-axis dimensions of hippocampal-cortical integration support memory function across the adult lifespan

5 months 3 weeks ago
The hippocampus is a complex structure critically involved in numerous behavior-regulating systems. In young adults, multiple overlapping spatial modes along its longitudinal and transverse axes describe the organization of its functional integration with neocortex, extending the traditional framework emphasizing functional differences between sharply segregated hippocampal subregions. Yet, it remains unknown whether these modes (i.e. gradients) persist across the adult human lifespan, and...
Kristin Nordin

Mapping out overlapping connectivity patterns

5 months 3 weeks ago
Untangling the functional organisation of a brain region crucial for memory and learning helps reveal how individual differences are linked to variations in recall ability, aging and dopamine receptor distribution.
Myrthe Faber

In Science Journals

5 months 3 weeks ago
Science, Volume 387, Issue 6740, Page 1264-1266, March 2025.
Michael Funk, and Bianca Lopez, Keith T. Smith, Phil Szuromi, Stella M. Hurtley, Madeleine Seale, Courtney Malo, Hannah Isles, Mattia Maroso, Sarah H. Ross, Ian S. Osborne, Jake S. Yeston, Jesse Smith, Sacha Vignieri, and Leslie K. Ferrarelli