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Moisture-responsive root-branching pathways identified in diverse maize breeding germplasm
Science, Volume 387, Issue 6734, Page 666-673, February 2025.
Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes
Science, Volume 387, Issue 6734, Page 674-682, February 2025.
Overwriting an instinct: Visual cortex instructs learning to suppress fear responses
Science, Volume 387, Issue 6734, Page 682-688, February 2025.
Does the mantis shrimp pack a phononic shield?
Science, Volume 387, Issue 6734, Page 659-666, February 2025.
Whale song shows language-like statistical structure
Science, Volume 387, Issue 6734, Page 649-653, February 2025.
Rapid and dynamic evolution of a giant Y chromosome in Silene latifolia
Science, Volume 387, Issue 6734, Page 637-643, February 2025.
The Silene latifolia genome and its giant Y chromosome
Science, Volume 387, Issue 6734, Page 630-636, February 2025.
Free speech, fact checking, and the right to accurate information
Science, Volume 387, Issue 6734, February 2025.
The future of measles
Science, Volume 387, Issue 6734, Page 585-585, February 2025.
Probing the planet’s poles
Science, Volume 387, Issue 6734, Page 584-584, February 2025.
HHMI kills program aimed at boosting inclusivity in STEM education
“Inclusive excellence” program had committed $60 million to 104 institutions
Humpback whale songs are structured like human language
Languagelike patterns in whale songs could make them easier for whales to learn
The fight against cholera is far from over. This Bangladeshi scientist is at the front lines
Firdausi Qadri hopes widespread use of cheap oral cholera vaccines can help vanquish an old scourge
Hole drilled into Greenland's heart reveals ice ready to slide into the sea
Unique drilling project has ominous implications for sea-level rise
News at a glance: Ebola vaccine test, asteroid watch, and China’s fusion laser lab
The latest in science and policy
Trump orders cause chaos at science agencies
Wild week of canceled meetings, program changes, and data purges creates high anxiety
An ancestor of ducks and geese paddled and dove alongside dinosaurs in Antarctica
Exquisite, fossilized skull sheds light on the evolutionary origins of waterfowl
Tiny tunnels bored by forest beetles could help fan wildfire flames
Long-overlooked insect architecture could cause forest fires to release more carbon
Sex-specific and cell-type-specific changes in chaperone-mediated autophagy across tissues during aging
Aging leads to progressive decline in organ and tissue integrity and function, partly due to loss of proteostasis and autophagy malfunctioning. A decrease with age in chaperone-mediated autophagy (CMA), a selective type of lysosomal degradation, has been reported in various organs and cells from rodents and humans. Disruption of CMA recapitulates features of aging, whereas activating CMA in mice protects against age-related diseases such as Alzheimer's, retinal degeneration and/or...
The emerging role of dysregulated propionate metabolism and methylmalonic acid in metabolic disease, aging, and cancer
Propionate metabolism dysregulation has emerged as a source of metabolic health alterations linked to aging, cardiovascular and renal diseases, obesity and diabetes, and cancer. This is supported by several large cohort population studies and recent work revealing its role in cancer progression. Mutations in several enzymes of this metabolic pathway are associated with devastating inborn errors of metabolism, resulting in severe methylmalonic and propionic acidemias. Beyond these rare diseases,...