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Critical habitat thresholds for effective pollinator conservation in agricultural landscapes
Science, Volume 389, Issue 6767, Page 1314-1319, September 2025.
Fiber-imaged supershear dynamics in the 2024 Mw 7 Mendocino Fault earthquake
Science, Volume 389, Issue 6767, Page 1361-1365, September 2025.
Deazaguanylation is a nucleobase-protein conjugation required for type IV CBASS immunity
Science, Volume 389, Issue 6767, Page 1347-1352, September 2025.
Quantum learning advantage on a scalable photonic platform
Science, Volume 389, Issue 6767, Page 1332-1335, September 2025.
Identification of short-range ordering motifs in semiconductors
Science, Volume 389, Issue 6767, Page 1342-1346, September 2025.
Global selection on insect antipredator coloration
Science, Volume 389, Issue 6767, Page 1336-1341, September 2025.
Fungus-farming termites can protect their crop by confining weeds with fungistatic soil boluses
Science, Volume 389, Issue 6767, Page 1366-1371, September 2025.
The phylogenetic position of the Yunxian cranium elucidates the origin of Homo longi and the Denisovans
Science, Volume 389, Issue 6767, Page 1320-1324, September 2025.
Lysosomes signal through the epigenome to regulate longevity across generations
Science, Volume 389, Issue 6767, Page 1353-1360, September 2025.
What to Expect When You're Dead: An Ancient Tour of Death and the Afterlife
Science, Volume 389, Issue 6767, Page 1299-1299, September 2025.
Why democracies die and what to do next
Science, Volume 389, Issue 6767, Page 1299-1299, September 2025.
The vitality of old age
Science, Volume 389, Issue 6767, Page 1298-1298, September 2025.
Ecuadorian scientists cleared of criminal charges in COVID-19 testing case
Prosecutors alleged officials and researchers defrauded government during the early months of the pandemic
Researchers are relieved at Trump’s likely pick for National Cancer Institute
Harvard physician-scientist Anthony Letai is poised to head world’s largest cancer research agency
How fungus-farming termites control weeds
Termites enlist microbes to defend their crops from undesirable fungi
Storied atom-smasher that makes tiny Big Bangs wraps up mission
For 26 years, the Relativistic Heavy Ion Collider has re-created the quark-gluon plasma that filled the infant universe
Thousands of quakes struck a major Greek volcano, mapping the plumbing beneath it
A “crisis” that rocked the island of Santorini may reveal a shared magma system between two volcanoes with explosive histories
Belgium program Enhancing the uptake and Effectiveness of a Multifactorial falls Prevention intervention in Older community-dWElling peRsons (BE-EMPOWERed): A study protocol
AIMS: This study protocol aims to outline a mixed-methods study of the implementation of the BE-EMPOWERed program in four primary care areas (PCAs) in Flanders. The study assesses implementation processes and outcomes, while exploring its effectiveness on clinical outcomes.
Gut-induced alpha-Synuclein and Tau propagation initiate Parkinson's and Alzheimer's disease co-pathology and behavior impairments
No abstract
CD103(-)CD8(+) T cells promote neurotoxic inflammation in Alzheimer's disease via granzyme K-PAR-1 signaling
Immune mechanisms contribute to the neuropathology of Alzheimer's disease (AD) but the role of adaptive immune cells is unclear. Here we show that the brain CD8^(+) T cell compartment is dysregulated in AD patients and in the 3xTg-AD mouse model, accumulating activated CD103^(-) tissue-resident memory T cells that produce large amounts of granzyme K (GrK). These CD103^(-)CD8^(+) T cells originate from the circulation and migrate into the brain using LFA-1 integrin. Ablation of brain...