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When Melodies Cue Memories: Electrophysiological Correlates of Autobiographically Salient Music Listening in Older Adults
Autobiographical memory is essential for older adults, providing a foundation for self-identity. Although healthy aging is accompanied by changes in memory retrieval, musical memory remains relatively unaffected, suggesting music may serve as a cue for autobiographical memory recall. Autobiographically salient (ABS) music (i.e., deeply encoded songs associated with significant people, places, and events) is posited to engage distinct memory processes from familiar (FAM) music (i.e., songs that...
Cisformer: a scalable cross-modality generation framework for decoding transcriptional regulation at single-cell resolution
Single-cell multiomic technologies enable the joint analysis of different modalities, but face challenges due to experimental complexity. Current computational methods for single-cell cross-modality translation lack biological interpretability. Here, we present Cisformer, a cross-attention-based generative model tailored for cross-modality generation between gene expression and chromatin accessibility at single-cell resolution. Systematic benchmarking demonstrates the superior accuracy and...
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Effect of Origanum majorana tea on oxidative stress biomarkers in Parkinson's disease: a randomized placebo-controlled pilot study
CONCLUSION: Origanum majorana infusion may enhance or regulate antioxidant status and reduce oxidative damage in patients with PD. Further studies are warranted to explore its potential therapeutic benefits.