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Federal judge to hear arguments relating to preliminary injunction to restore funding for other UC grants

Other publishing proposals would scrap reimbursements or pay peer reviewers, unprecedented steps for a major government funder

A former head of the Bureau of Labor Statistics rebuts reason why president fired the agency’s leader

In first human test, genetically modified pancreas cells injected into patient’s arm evade immune attack, produce insulin

Discovery of a bacterium could reveal more about massive die-off, perhaps aid recovery

Parkinson's Disease (PD) is an incurable neurodegenerative disease that causes movement disorders. Neurons in PD aggregate α-synuclein and are depleted from the substantia nigra (SN), which is a movement control hub. The presence of α-synuclein-reactive T cells in PD patient blood suggests a role for adaptive immunity in the pathogenesis of PD. However, the characteristics of this response within the brain are not well understood. Here, we employed single-nucleus RNAseq, spatial transcriptomics,...

Caloric restriction slows or prevents Alzheimer's disease in animal models. Calorie restriction is typically implemented in rodents through feeding once per day; as the animals quickly consume their food, they are subject to a prolonged self-imposed fasting period between meals. Here, we examine the distinct contributions of fasting and reduced calories to the beneficial effects of calorie restriction on Alzheimer's disease by placing male and female 3xTg and non-transgenic control mice on a...