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Immunosenescence and its impact on ischemic stroke risk and outcomes in older adults: a systematic review
CONCLUSION: Immunosenescence plays a crucial role in IS pathogenesis and recovery, with chronic inflammation and immune dysfunction exacerbating stroke outcomes in older adults. Targeting immune markers, particularly IL-6 and the Th17/Treg imbalance, may offer new therapeutic approaches to improve stroke prognosis in aging populations. Further research is needed to develop interventions that address immunosenescence in IS.
Nightly variations in sleep quality and next-day cognitive performance: an in-home study in healthy older adults
INTRODUCTION: Sleep quality is often thought to be a key determinant of cognitive performance, particularly in older adults who experience age-related changes in sleep architecture. However, the extent to which nightly variations in sleep quality impact next-day cognitive performance remains unclear-in part because it has only recently become practical to measure sleep over multiple nights.