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Bound by a handshake

3 months 1 week ago
Science, Volume 391, Issue 6789, Page 988-989, March 2026.
Moritz T. Meyer and Howard Griffiths

In Other Journals

3 months 1 week ago
Science, Volume 391, Issue 6789, Page 1001-1002, March 2026.
Corinne Simonti, and Jesse Smith, Sarah H. Ross, Cheri Sirois, Bianca Lopez, Jelena Stajic, Di Jiang, Michael A. Funk, and Sumin Jin

Planting a seed

3 months 1 week ago
Science, Volume 391, Issue 6789, Page 1078-1078, March 2026.
Gilberto Lopez

Science stories for young readers

3 months 1 week ago
Science, Volume 391, Issue 6789, Page 978-984, March 2026.
Lauren Kmec, Jennie Erin Smith, Valerie Thompson, Michael Funk, Keith T. Smith, Jennifer Sills, Madeleine Seale, Chloe Seale, Alice Seale, Matthew Warren, Kiaan Suri-Warren, Bianca Buehler, Christie Wilcox, Yevgeniya Nusinovich, Isaac Nusinovich Ucko,…

Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease

3 months 1 week ago
Parkinson's disease (PD) is a prevalent neurodegenerative disorder predominantly affecting individuals over 60. Its motor symptoms stem from the deterioration of dopaminergic neurons within the substantia nigra. Despite aging being a significant risk factor, the specific mechanisms linking aging and PD pathology remain unclear. Leveraging advancements in single-cell genomics, this study utilizes single-nucleus multiome sequencing to capture transcriptomic and epigenetic profiles from 40,125...
Kangli Wang