Nature Aging
Old enlarged nucleoli open the door to the cell’s demise
A mortality timer based on nucleolar size triggers nucleolar integrity loss and catastrophic genomic instability
Comprehensive single-cell aging atlas of healthy mammary tissues reveals shared epigenomic and transcriptomic signatures of aging and cancer
Transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states
Molecular and genetic insights into human ovarian aging from single-nuclei multi-omics analyses
Linking ferroptosis to thymic involution
Mapping aged stem cell states associated with decline in skeletal muscle regeneration
Exome sequencing in Asian populations identifies low-frequency and rare coding variation influencing Parkinson’s disease risk
Boosting NAD<sup>+</sup> in patients with COPD reduces airway inflammation
Dysregulation of endogenous retroviruses triggers aging and senescence
Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
Reactivation of senescence-associated endogenous retroviruses by ATF3 drives interferon signaling in aging
Clearance of <i>p21</i> highly expressing senescent cells accelerates cutaneous wound healing
Diagnosis of Alzheimer’s disease using plasma biomarkers adjusted to clinical probability
Chronic social stress induces p16-mediated senescent cell accumulation in mice
Cell type-divergent functions of senescence
Modifiable risk factors of dementia in Latin America
Phenome-wide associations of human aging uncover sex-specific dynamics
Lessons from the HEALEY adaptive platform trial in amyotrophic lateral sclerosis
How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
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