Traditional Disease Risk Factors Outperform Epigenetic Clocks as Predictors of Non-Communicable Disease Morbidity in a Middle-Aged Cohort Aging & Longevity
Age-associated DNA methylation patterns in mouse blood and tail: feasibility of tissue-specific epigenetic clock development Aging & Longevity
Distribution, inequalities and associated factors of unmet medical needs among older adults: evidence from the national health service survey Aging & Longevity
Building Sustainable Access to Home- and Community-Based Services for Rural Veterans and Older Americans Aging & Longevity
ZBTB7A-mediated regulation of astrocytic glycolysis in neurodegenerative diseases: insights from literature review and bioinformatics prediction Aging & Longevity
Exogenous mitochondrial transplantation attenuates oxidative stress-driven retinal degeneration in a sodium iodate - induced mouse model Aging & Longevity
Systemic infections alter cortical transcriptional signatures in Alzheimer's disease Aging & Longevity
Epigenetic aging is associated with hearing loss and multi-system disease risk independently of chronological age Aging & Longevity
The Autophagy-Senescence-Inflammasome Axis: A Novel Triad in Neurodegenerative Diseases? Aging & Longevity
‘This time, it’s the other way around’: how Indonesia is reclaiming the science of human history Nature News
British ‘First Fleet’ brought smallpox to Australia—and may have killed millions Science Daily Headlines
As flu virus threatens its unique bird species, New Zealand pins hopes on a vaccine Science Daily Headlines
TTF2 processes sites of incomplete DNA replication during mitosis via sister-chromatid exchanges Science
Manipulation of protein translation and stem cell self-renewal by CRISPR activation of rRNA transcription Science
The origin, history, and resistance architecture of an invasive urban malaria mosquito in Africa Science
Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle Nature Aging
Therapeutic targeting of the conserved region within the low-complexity domain of TDP-43 is neuroprotective and extends survival in amyotrophic lateral sclerosis mice Nature Aging
Mapping the network architecture of aging to identify repurposable drug candidates for longevity Nature Aging
Therapeutic inhibition of telomeric DNA damage response rescues hematopoietic dysfunction driven by telomere shortening and aging Nature Aging
Associations of proteomic age clocks with lifestyle risk factors, incident chronic diseases and mortality in two European cohorts Nature Aging
NAD(+) modulates REST isoform expression and its downstream mitophagy in Alzheimer's disease Alzheimer & Parkinson
The Autophagy-Senescence-Inflammasome Axis: A Novel Triad in Neurodegenerative Diseases? Alzheimer & Parkinson
ACE2 deficiency alters brain RAS signaling to induce pro-inflammatory microglial remodeling and Worsen Parkinson's disease pathology Alzheimer & Parkinson
Dopamine-driven mitochondrial reverse electron transport in immune cells mediates gut-brain ROS signaling during sleep deprivation Alzheimer & Parkinson
Targeting of CH25H to boost p62-dependent autophagic degradation of alpha-synuclein in cell and mouse models of Parkinson's disease Alzheimer & Parkinson
Autosomal allelic inactivation at loci with variable replication timing and dosage sensitivity Alzheimer & Parkinson
Restoring the balance: Resistance exercise-induced insulin-like growth factor-1 restores PI3K/Akt and MAPK/ERK cross-talk to ameliorate Alzheimer's disease Alzheimer & Parkinson
Cryo-EM structure of soluble VPS13C suggests its regulation by a conformational switch and by calmodulin Alzheimer & Parkinson
Preventative semaglutide and tirzepatide treatment does not alter disease progression in the 5xFAD mouse model of Alzheimer's disease Alzheimer & Parkinson
Can't stick to a diet? Intermittent fasting may be easier than counting calories for weight loss ScienceDaily Health
