Map-based spatial perspective taking reveals frontal late negativity loss and posterior delta gain in mild cognitive impairment Aging & Longevity
Aging-associated decline of phosphatidylcholine synthesis is a malleable trigger of natural mitochondrial aging Aging & Longevity
Dose-dependent mitochondrial H(2)O(2) signaling drives toxicity or stress adaptation and longevity in fission yeast Aging & Longevity
Multi-omic profiling reveals pericyte and smooth muscle cell contributions to CADASIL pathology in cell-specific Notch3 mutant mice Aging & Longevity
FOXF1/2 establish a senescence-specific enhancer landscape to activate the pro-inflammatory senescence-associated secretory phenotype Aging & Longevity
Bedrest, frailty and exercise countermeasures: A 14-day head-down tilt study in mid-older aged adults Aging & Longevity
Magnetic muon measurements and gene-therapy advances win US$3 million Breakthrough prizes Nature News
Quantum computers take on health care: light-sensitive cancer drugs win US$2-million contest Nature News
Severe malaria may affect children’s cognitive abilities more than a decade later Science Daily Headlines
As helium-3 runs scarce, researchers seek new ways to chill quantum computers Science Daily Headlines
Grand canyon’s origin resolved? Ancient lake's flood may have etched famed gorge Science Daily Headlines
Today’s robots walk, swim, fly, and manipulate objects on the go—and they’re just getting started Science
Gas-depleted planet formation occurred in the four-planet system around the red dwarf LHS 1903 Science
p21<sup>+</sup>TREM2<sup>+</sup> senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease Nature Aging
Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging Nature Aging
Single-cell analysis of the human immune system reveals sex-specific dynamics of immunosenescence Nature Aging
Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging Nature Aging
Neuronal APOE4-induced early hippocampal network hyperexcitability in Alzheimer’s disease pathogenesis Nature Aging
Multiomic single-cell perturbation screens reveal critical lncRNA regulators of senescence Nature Aging
Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression Alzheimer & Parkinson
Single-nucleus brain transcriptomics reveals microglia dysfunction in multiple system atrophy Alzheimer & Parkinson
Variants in the proteasome regulator PSMF1 cause a phenotypic spectrum from parkinsonism to perinatal lethality Alzheimer & Parkinson
Amyloid-beta-driven glymphatic dysfunction in Alzheimer's disease model mice is driven by Ca(2+)-mediated increases in astrocytic cholesterol Alzheimer & Parkinson
An acetylated Tau-174 CSF biomarker discriminates between TDP-43 and tau pathology in patients with frontotemporal lobar degeneration Alzheimer & Parkinson
Plasma phosphorylated tau 217 and longitudinal trajectories of Aβ, tau, and cognition in cognitively unimpaired older adults Alzheimer & Parkinson
Signaling cascades shape functional subpopulations of cortical astrocytes in male wild-type mice and APP/PS1dE9 Alzheimer's disease model Alzheimer & Parkinson
