Nature Aging
Network-driven discovery of repurposable drugs targeting hallmarks of aging
The blood metabolome of brain health in midlife and influences of genes, microbiome and exposome
Hierarchical endpoints and win statistics for geromedicine trials
Epigenetic clocks as quantitative readouts of epigenetic drift
Circulating metabolites at the crossroads of lifestyle and brain health
Are GLP-1 receptor agonists gerotherapeutics or just treatments for obesity?
Reaching for the cure as progeria research comes of age at the 12th international scientific workshop
Aging disrupts spatiotemporal coordination in the cycling murine ovary
Profiling the molecular and physiological effects of senolytic treatment on aged mice identifies immune, fibrotic and metabolic remodeling
Nuclear export of R-loop by the DDX1 and XPO1 complex promotes senescence-associated secretory phenotype and inflammaging
A need for pragmatism in preclinical aging and longevity research
Two modes of aging to explain why lifespans differ across species
Author Correction: Exercise alleviates cognitive dysfunction in Alzheimer’s disease mice via skeletal muscle-derived extracellular vesicles that enhance plaque clearance by microglia
An open competition for biomarkers of aging
Single-nucleus interrogation of primate small intestinal aging reveals NCoR1 decline as a conserved feature that is reversed by metformin
A damage accumulation model identifies distinct aging regimes across species
Systematic review assesses link between physical activity and epigenetic age
Time-restricted feeding puts mouse healthspan on the clock
Time-restricted feeding extends healthspan in both sexes and lifespan in male C57BL/6 J mice
DREAM repressive activity links somatic mutation, lifespan and disease
How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
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