Nature Aging
Author Correction: Destabilizing heterochromatin by APOE mediates senescence
Aging rises, yet the double burden of illness remains
A consensus roadmap from the SENESCENCE2030 network towards precision senescence medicine
GLP-1 receptor agonism extends median lifespan in mice
Reframing the epidemiological transition as increasing returns to tackling aging-related diseases
Mapping structural aging across human tissues reveals tissue-specific trajectories and coordinated deterioration
Multimorbidity patterns influence mobility disability prevention in frail older adults from the SPRINTT trial
Mitochondrial DNA leakage in oocytes activates cGAS-STING signaling to drive ovarian aging
Leaky oocytes propagate cGAS–STING signaling
Closing the gap in Alzheimer’s disease research through the Sex | Gender in Neurodegeneration Consortium
Contractile myografts confer systemic anti-aging benefits
Cytotoxic CD4<sup>+</sup> T cells induce age-associated myelopoiesis through CCL5–CCR5 signaling
Contracting myografts mimic exercise response
Loss of cGAS disrupts H3K9me3 organization and derepresses LINE1 to cause inflammaging
A geroprotective probiotic and its functional metabolite counteract inflammaging to extend healthspan
Sex-specific aging clocks from a large-scale human phenome reveal distinct aging transitions and circulating signatures
cGAS-deficient mice display premature aging associated with derepression of LINE1 elements and inflammation
Longevity medicine cuts ‘desire paths’ in primary care
Inhibiting cyclin D1–CDK6 suppresses senescence-associated inflammatory gene expression and age-related functional decline
Turning CDK4/6 inhibitors against the dark side of senescence
How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the connection between aging and disease? Can we predict the evolving trends in the aging of human populations and prepare our societies for what has been called the Silver Tsunami? These are some of the important questions that the broad field of aging research is trying to address and that together form one of the Grand Challenges of the twenty-first century. The mission of Nature Aging is to provide a unique multidisciplinary, unifying and highly visible publishing platform for the aging-research community. The journal is highly selective yet broad in its coverage, publishing research from across the entire spectrum of the field, ranging from the basic biology of aging to the impact of aging on society. The journal aims to foster interactions among different areas of this diverse field of research and to promote new and exciting ideas within and beyond the research community, to enable synergy and maximize scientific and societal impact.
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