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Food-industry waste finds a second life as bioplastic
Judge backs USAID, EPA research targeted, NIH comings and goings: Trump Tracker
Follow President Donald Trump’s impact on U.S. research and science globally
Cleaning up space: how satellites and telescopes can live together
Governments must stop hoarding climate data
Catchy, clear, concise: three-part phrases boost research paper citations
Swarms of satellites are harming astronomy. Here’s how researchers are fighting back
An experiment in mass education using satellite TV
Structures and mechanism of human mitochondrial pyruvate carrier
Space debris is falling from the skies. We need to tackle this growing danger
Japan needs a fresh approach to innovation
AI demands a different approach to education
Global cooperation is crucial for DeepSeek and broader AI research
US disruptions to science could transform global research landscape
Author Correction: Endocytosis in the axon initial segment maintains neuronal polarity
Outgoing head of heralded U.S. global HIV/AIDS program urges Trump to reverse cuts
John Nkengasong, who had helmed PEPFAR since 2022, says “history will remember we showed humanity”
After Columbia’s ‘nightmare,’ dozens more universities brace for Trump NIH cuts
Threats to end funding over alleged antisemitism are rocking medical researchers—and stoking calls for legal action
Scorching volcanic ash preserved ancient vulture in stunning detail
Superfine zeolite crystals captured feathery details such as color and shape
Potential therapeutic targets for Alzheimer's disease: Fibroblast growth factors and their regulation of ferroptosis, pyroptosis and autophagy
Alzheimer's disease (AD) is a progressively worsening neurodegenerative disorder characterized primarily by the deposition of amyloid beta (Aβ) plaques in the brain and the abnormal aggregation of tau protein forming neurofibrillary tangles. These pathological changes lead to impaired neuronal function and cell death, subsequently affecting the structure and function of the brain. Fibroblast growth factors (FGFs) are a group of proteins that play crucial roles in various biological processes,...
Prevention of cardiovascular disease for healthy aging and longevity: A new scoring system and related "mechanisms-hallmarks-biomarkers"
Healthy "environment-sleep-emotion-exercise-diet" intervention [E(e)SEEDi] lifestyle can improve the quality of life, prolong aging and promote longevity due to improvement of human immunity and prevention of cardiovascular diseases (CVD). Here, the author reviewed the associations between these core elements with CVD and cardiovascular aging, and developed a new scoring system based on the healthy E(e)SEEDi lifestyle for prediction and evaluation of life expectancy. These core factors are...
Atg5 in microglia regulates sex-specific effects on postnatal neurogenesis in Alzheimer's disease
Female Alzheimer's disease (AD) patients display greater cognitive deficits and worse AD pathology as compared to male AD patients. In this study, we found that conditional knockout (cKO) of Atg5 in female microglia failed to obtain disease-associated microglia (DAM) gene signatures in familiar AD mouse model (5xFAD). Next, we analyzed the maintenance and neurogenesis of neural stem cells (NSCs) in the hippocampus and subventricular zone (SVZ) from 5xFAD mice with Atg5 cKO. Our data indicated...